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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLOT2
All Species:
27.27
Human Site:
S165
Identified Species:
54.55
UniProt:
Q14254
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14254
NP_004466.2
428
47064
S165
Y
D
K
V
D
Y
L
S
S
L
G
K
T
Q
T
Chimpanzee
Pan troglodytes
Q7YR41
427
47395
H162
H
D
D
Q
D
Y
L
H
S
L
G
K
A
R
T
Rhesus Macaque
Macaca mulatta
XP_001107301
412
45109
S149
Y
D
K
V
D
Y
L
S
S
L
G
K
T
Q
T
Dog
Lupus familis
XP_853652
480
52241
S217
Y
D
K
V
D
Y
L
S
S
L
G
K
T
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
O08917
428
47495
H162
H
D
D
Q
D
Y
L
H
S
L
G
K
A
R
T
Rat
Rattus norvegicus
Q9Z2S9
428
47020
S165
Y
D
K
V
D
Y
L
S
S
L
G
K
T
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505411
321
36000
S148
Y
D
K
V
E
Y
L
S
S
L
G
K
T
Q
T
Chicken
Gallus gallus
NP_001025890
330
36186
L145
E
A
Q
L
A
Y
E
L
Q
S
A
R
E
Q
Q
Frog
Xenopus laevis
Q5XH03
335
37273
Q166
M
A
P
G
I
I
I
Q
A
V
R
V
T
K
P
Zebra Danio
Brachydanio rerio
Q98TZ8
428
46903
S165
Y
D
K
V
D
Y
L
S
S
L
G
K
S
Q
T
Tiger Blowfish
Takifugu rubipres
NP_001092131
429
47170
S165
Y
D
K
V
E
Y
L
S
S
L
G
K
T
Q
T
Fruit Fly
Dros. melanogaster
O61492
438
48139
A178
Y
D
D
V
Q
Y
L
A
S
L
G
K
A
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.4
91.8
88.3
N.A.
47.4
99.3
N.A.
70.5
67
21.9
80.6
80.4
63.9
N.A.
N.A.
N.A.
Protein Similarity:
100
70.5
92.7
88.5
N.A.
70.3
99.5
N.A.
73.1
73.3
38.3
91.3
90.9
80.5
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
60
100
N.A.
93.3
13.3
6.6
93.3
93.3
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
73.3
100
N.A.
100
33.3
33.3
100
100
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
0
9
9
0
9
0
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
84
25
0
59
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
17
0
9
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
84
0
0
0
0
% G
% His:
17
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
59
0
0
0
0
0
0
0
0
84
0
9
0
% K
% Leu:
0
0
0
9
0
0
84
9
0
84
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
9
17
9
0
0
9
9
0
0
0
0
75
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
9
0
17
0
% R
% Ser:
0
0
0
0
0
0
0
59
84
9
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
59
0
84
% T
% Val:
0
0
0
67
0
0
0
0
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _