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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLOT2 All Species: 13.64
Human Site: S224 Identified Species: 27.27
UniProt: Q14254 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14254 NP_004466.2 428 47064 S224 R A F E L Q K S A F S E E V N
Chimpanzee Pan troglodytes Q7YR41 427 47395 A221 R D Y E L K K A A Y D I E V N
Rhesus Macaque Macaca mulatta XP_001107301 412 45109 S208 R A F E L Q K S A F S E E V N
Dog Lupus familis XP_853652 480 52241 S276 R A F E L Q K S A F S E E V N
Cat Felis silvestris
Mouse Mus musculus O08917 428 47495 A221 R D Y E L K K A T Y D I E V N
Rat Rattus norvegicus Q9Z2S9 428 47020 S224 R A F E L Q K S A F S E E V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505411 321 36000 L185 A E C K R E M L D I K F Q A D
Chicken Gallus gallus NP_001025890 330 36186 E181 E K E I I R K E K E L I A T V
Frog Xenopus laevis Q5XH03 335 37273 K205 Q K Q K V V E K E A E T E R K
Zebra Danio Brachydanio rerio Q98TZ8 428 46903 A224 R E L E M Q K A A F N Q E V N
Tiger Blowfish Takifugu rubipres NP_001092131 429 47170 A224 R E L E M Q K A S F N Q E V N
Fruit Fly Dros. melanogaster O61492 438 48139 A237 R M Y K L Q K A N F D Q E I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.4 91.8 88.3 N.A. 47.4 99.3 N.A. 70.5 67 21.9 80.6 80.4 63.9 N.A. N.A. N.A.
Protein Similarity: 100 70.5 92.7 88.5 N.A. 70.3 99.5 N.A. 73.1 73.3 38.3 91.3 90.9 80.5 N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 100 N.A. 46.6 100 N.A. 0 6.6 6.6 60 53.3 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 80 100 100 N.A. 73.3 100 N.A. 26.6 20 33.3 86.6 86.6 80 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 34 0 0 0 0 0 42 50 9 0 0 9 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 0 0 9 0 25 0 0 0 9 % D
% Glu: 9 25 9 67 0 9 9 9 9 9 9 34 84 0 0 % E
% Phe: 0 0 34 0 0 0 0 0 0 59 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 0 9 0 25 0 9 0 % I
% Lys: 0 17 0 25 0 17 84 9 9 0 9 0 0 0 9 % K
% Leu: 0 0 17 0 59 0 0 9 0 0 9 0 0 0 0 % L
% Met: 0 9 0 0 17 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 75 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 9 0 0 59 0 0 0 0 0 25 9 0 0 % Q
% Arg: 75 0 0 0 9 9 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 0 0 0 0 34 9 0 34 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 0 9 0 9 0 % T
% Val: 0 0 0 0 9 9 0 0 0 0 0 0 0 67 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 25 0 0 0 0 0 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _