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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM25 All Species: 12.42
Human Site: Y463 Identified Species: 39.05
UniProt: Q14258 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14258 NP_005073.2 630 70989 Y463 Y I K V I L D Y N T A H N K V
Chimpanzee Pan troglodytes Q1XHU0 518 59727 R365 S V K F V E T R L R D L P D T
Rhesus Macaque Macaca mulatta XP_001101634 750 83055 Y583 Y V K V I L D Y N T A H N K V
Dog Lupus familis XP_548223 630 70261 Y463 A V K F S L D Y N T A H N K V
Cat Felis silvestris
Mouse Mus musculus Q61510 634 71754 Y468 F V K V I F D Y N T A H N K V
Rat Rattus norvegicus Q6MFZ5 488 56376 R335 S V K F V E T R L R D L P D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415653 633 71406 F469 A A N V T L D F N T A H S K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956469 654 74275 V486 G T I L H F D V R T A H K R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.3 79.7 76.8 N.A. 73.3 23.4 N.A. N.A. 49.1 N.A. 33.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 39.5 81.3 85.4 N.A. 83.1 39.3 N.A. N.A. 67.3 N.A. 53.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 73.3 N.A. 80 6.6 N.A. N.A. 60 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 80 N.A. 93.3 20 N.A. N.A. 73.3 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 13 0 0 0 0 0 0 0 0 75 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 75 0 0 0 25 0 0 25 0 % D
% Glu: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % E
% Phe: 13 0 0 38 0 25 0 13 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 75 0 0 0 % H
% Ile: 0 13 13 0 38 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 75 0 0 0 0 0 0 0 0 0 13 63 0 % K
% Leu: 0 0 0 13 0 50 0 0 25 0 0 25 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 13 0 0 0 0 0 63 0 0 0 50 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 25 13 25 0 0 0 13 0 % R
% Ser: 25 0 0 0 13 0 0 0 0 0 0 0 13 0 0 % S
% Thr: 0 13 0 0 13 0 25 0 0 75 0 0 0 0 25 % T
% Val: 0 63 0 50 25 0 0 13 0 0 0 0 0 0 63 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 25 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _