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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM25
All Species:
12.42
Human Site:
Y463
Identified Species:
39.05
UniProt:
Q14258
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14258
NP_005073.2
630
70989
Y463
Y
I
K
V
I
L
D
Y
N
T
A
H
N
K
V
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
R365
S
V
K
F
V
E
T
R
L
R
D
L
P
D
T
Rhesus Macaque
Macaca mulatta
XP_001101634
750
83055
Y583
Y
V
K
V
I
L
D
Y
N
T
A
H
N
K
V
Dog
Lupus familis
XP_548223
630
70261
Y463
A
V
K
F
S
L
D
Y
N
T
A
H
N
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61510
634
71754
Y468
F
V
K
V
I
F
D
Y
N
T
A
H
N
K
V
Rat
Rattus norvegicus
Q6MFZ5
488
56376
R335
S
V
K
F
V
E
T
R
L
R
D
L
P
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415653
633
71406
F469
A
A
N
V
T
L
D
F
N
T
A
H
S
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956469
654
74275
V486
G
T
I
L
H
F
D
V
R
T
A
H
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.3
79.7
76.8
N.A.
73.3
23.4
N.A.
N.A.
49.1
N.A.
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.5
81.3
85.4
N.A.
83.1
39.3
N.A.
N.A.
67.3
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
73.3
N.A.
80
6.6
N.A.
N.A.
60
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
80
N.A.
93.3
20
N.A.
N.A.
73.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
13
0
0
0
0
0
0
0
0
75
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
75
0
0
0
25
0
0
25
0
% D
% Glu:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% E
% Phe:
13
0
0
38
0
25
0
13
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
75
0
0
0
% H
% Ile:
0
13
13
0
38
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
75
0
0
0
0
0
0
0
0
0
13
63
0
% K
% Leu:
0
0
0
13
0
50
0
0
25
0
0
25
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
63
0
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
25
13
25
0
0
0
13
0
% R
% Ser:
25
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% S
% Thr:
0
13
0
0
13
0
25
0
0
75
0
0
0
0
25
% T
% Val:
0
63
0
50
25
0
0
13
0
0
0
0
0
0
63
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _