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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTK2B
All Species:
19.09
Human Site:
S389
Identified Species:
46.67
UniProt:
Q14289
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14289
NP_004094.3
1009
115875
S389
L
N
L
E
A
R
R
S
H
L
S
E
S
C
S
Chimpanzee
Pan troglodytes
XP_001163273
1009
115819
S389
L
N
L
E
A
R
R
S
H
L
S
E
S
C
S
Rhesus Macaque
Macaca mulatta
XP_001108903
1009
115932
S389
L
N
L
E
A
R
R
S
H
F
S
E
S
C
S
Dog
Lupus familis
XP_543228
1009
115827
P389
L
N
L
E
A
Q
R
P
H
L
S
E
S
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QVP9
1009
115804
S389
L
N
L
E
A
R
R
S
H
L
S
E
S
C
S
Rat
Rattus norvegicus
P70600
1009
115766
S389
L
N
L
E
S
R
R
S
H
L
S
E
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515547
835
95017
G312
I
M
E
L
Y
P
F
G
E
L
G
H
Y
L
E
Chicken
Gallus gallus
Q00944
1053
119189
R385
N
N
E
K
Q
G
V
R
S
H
T
V
S
V
S
Frog
Xenopus laevis
Q91738
1068
121137
R385
N
N
E
K
H
G
V
R
P
H
A
V
S
V
S
Zebra Danio
Brachydanio rerio
NP_997735
1004
113974
T385
E
I
P
S
G
K
K
T
D
S
F
R
Y
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
96.2
N.A.
95.5
95.6
N.A.
63.1
44.8
43.8
59.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.5
98.8
N.A.
98.1
98.1
N.A.
70
62.2
61.7
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
100
93.3
N.A.
6.6
20
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
100
N.A.
13.3
33.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
30
60
0
0
0
0
10
0
0
60
0
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
20
0
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
60
20
0
10
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
20
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
60
0
60
10
0
0
0
0
0
60
0
0
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
80
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
0
0
10
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
50
60
20
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
10
0
0
50
10
10
60
0
80
10
80
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
20
0
0
0
0
20
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _