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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLNC All Species: 22.12
Human Site: S2415 Identified Species: 81.11
UniProt: Q14315 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14315 NP_001120959.1 2725 291022 S2415 A R R L T V T S L Q E T G L K
Chimpanzee Pan troglodytes XP_519364 2571 275851 A2264 G P L G E G G A H K V R A G G
Rhesus Macaque Macaca mulatta XP_001090724 2619 277967 S2311 A R R L T V S S L Q E S G L K
Dog Lupus familis XP_539385 2720 290314 S2410 A R R L T V T S L Q E T G L K
Cat Felis silvestris
Mouse Mus musculus Q8VHX6 2726 291101 S2416 A R R L T V T S L Q E T G L K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508334 2693 287074 S2385 A R R L T V S S L Q E S G L K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666982 2702 289756 S2391 A R R L T V T S L Q E K D L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.8 70.7 98 N.A. 98.2 N.A. N.A. 71.7 N.A. N.A. 78.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 86.7 82.2 98.7 N.A. 99 N.A. N.A. 82.9 N.A. N.A. 87.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 86.6 100 N.A. 100 N.A. N.A. 86.6 N.A. N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 N.A. N.A. 100 N.A. N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 86 0 0 0 0 0 0 15 0 0 0 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % D
% Glu: 0 0 0 0 15 0 0 0 0 0 86 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 15 0 15 15 0 0 0 0 0 72 15 15 % G
% His: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 15 0 15 0 0 86 % K
% Leu: 0 0 15 86 0 0 0 0 86 0 0 0 0 86 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 % Q
% Arg: 0 86 86 0 0 0 0 0 0 0 0 15 0 0 0 % R
% Ser: 0 0 0 0 0 0 29 86 0 0 0 29 0 0 0 % S
% Thr: 0 0 0 0 86 0 58 0 0 0 0 43 0 0 0 % T
% Val: 0 0 0 0 0 86 0 0 0 0 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _