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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM50A
All Species:
43.03
Human Site:
S121
Identified Species:
78.89
UniProt:
Q14320
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14320
NP_004690.1
339
40242
S121
K
R
K
I
S
S
L
S
F
T
L
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001146118
452
50373
S234
K
R
K
I
S
S
L
S
F
T
L
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001093745
339
40251
S121
K
R
K
I
S
S
L
S
F
T
L
E
E
E
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV03
339
40233
S121
K
R
K
I
S
S
L
S
F
T
L
E
E
E
E
Rat
Rattus norvegicus
NP_001164044
339
40191
S121
K
R
K
I
S
S
L
S
F
T
L
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518058
312
37095
S84
K
R
K
I
S
S
L
S
F
T
L
D
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLV7
343
40764
S121
K
R
K
I
A
S
L
S
F
N
L
E
E
D
E
Zebra Danio
Brachydanio rerio
Q568K9
341
40523
S121
K
R
K
I
A
S
L
S
F
N
P
D
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAY7
359
42838
S120
K
R
Q
I
Q
A
L
S
F
N
L
D
D
D
E
Honey Bee
Apis mellifera
XP_624083
345
40901
S120
K
K
Q
I
Q
A
L
S
F
N
L
Y
E
D
E
Nematode Worm
Caenorhab. elegans
Q18691
326
37886
E105
S
Q
E
A
R
E
K
E
E
H
V
A
K
H
T
Sea Urchin
Strong. purpuratus
XP_001183761
318
37639
S113
L
K
N
A
G
T
L
S
F
N
M
D
E
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H110
337
39221
S119
K
K
R
K
I
K
G
S
S
R
L
S
F
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
99.7
N.A.
N.A.
98.2
98.5
N.A.
84.6
N.A.
87.4
86.2
N.A.
62.6
62.6
45.4
66.6
Protein Similarity:
100
74.7
99.7
N.A.
N.A.
99.4
99.7
N.A.
87
N.A.
92.7
94.1
N.A.
79.9
79.7
66
82.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
N.A.
80
66.6
N.A.
53.3
53.3
0
33.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
N.A.
93.3
80
N.A.
86.6
80
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
16
16
0
0
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
31
8
31
0
% D
% Glu:
0
0
8
0
0
8
0
8
8
0
0
47
77
47
93
% E
% Phe:
0
0
0
0
0
0
0
0
85
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
77
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
85
24
62
8
0
8
8
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
0
0
0
0
85
0
0
0
77
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
39
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
16
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
70
8
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
47
62
0
93
8
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
47
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _