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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM50A All Species: 42.73
Human Site: S62 Identified Species: 78.33
UniProt: Q14320 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14320 NP_004690.1 339 40242 S62 A V E A E L K S S T V G L V T
Chimpanzee Pan troglodytes XP_001146118 452 50373 S175 A V E A E L K S S T V G L V T
Rhesus Macaque Macaca mulatta XP_001093745 339 40251 S62 A V E A E L K S S T V G L V T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WV03 339 40233 S62 A V E A E L K S S T V G L V T
Rat Rattus norvegicus NP_001164044 339 40191 S62 A V E A E L K S S T V G L V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518058 312 37095 V44 K A K Q E A L V K E R E K Q L
Chicken Gallus gallus
Frog Xenopus laevis Q4KLV7 343 40764 S62 A V E A E L K S S T V G L V T
Zebra Danio Brachydanio rerio Q568K9 341 40523 S62 A V E Q E L K S S T V G L V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAY7 359 42838 S61 A V E Q Q L K S S T I G L V T
Honey Bee Apis mellifera XP_624083 345 40901 T61 A V E Q Q L K T S T I G L V T
Nematode Worm Caenorhab. elegans Q18691 326 37886 S58 T V E E V V K S K T Y G L V S
Sea Urchin Strong. purpuratus XP_001183761 318 37639 S63 A V E Q Q L K S S T I G L V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H110 337 39221 K65 I L D T A F K K E T V G L V T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.7 99.7 N.A. N.A. 98.2 98.5 N.A. 84.6 N.A. 87.4 86.2 N.A. 62.6 62.6 45.4 66.6
Protein Similarity: 100 74.7 99.7 N.A. N.A. 99.4 99.7 N.A. 87 N.A. 92.7 94.1 N.A. 79.9 79.7 66 82.6
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 6.6 N.A. 100 93.3 N.A. 80 73.3 53.3 80
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 N.A. 100 93.3 N.A. 93.3 93.3 66.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 46.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 69.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 77 8 0 47 8 8 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 85 8 62 0 0 0 8 8 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 24 0 0 0 0 % I
% Lys: 8 0 8 0 0 0 93 8 16 0 0 0 8 0 0 % K
% Leu: 0 8 0 0 0 77 8 0 0 0 0 0 93 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 39 24 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 77 77 0 0 0 0 0 8 % S
% Thr: 8 0 0 8 0 0 0 8 0 93 0 0 0 0 85 % T
% Val: 0 85 0 0 8 8 0 8 0 0 62 0 0 93 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _