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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM50A
All Species:
16.97
Human Site:
Y140
Identified Species:
31.11
UniProt:
Q14320
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14320
NP_004690.1
339
40242
Y140
E
E
E
E
A
A
M
Y
E
E
E
M
E
R
E
Chimpanzee
Pan troglodytes
XP_001146118
452
50373
Y253
E
E
E
E
A
A
M
Y
E
E
E
M
E
G
E
Rhesus Macaque
Macaca mulatta
XP_001093745
339
40251
Y140
E
E
E
E
V
A
M
Y
E
E
E
M
E
R
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV03
339
40233
Y140
E
E
E
E
M
A
M
Y
E
E
E
L
E
R
E
Rat
Rattus norvegicus
NP_001164044
339
40191
Y140
E
E
E
E
M
A
M
Y
E
E
E
L
E
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518058
312
37095
D102
E
E
E
E
D
D
V
D
E
E
E
L
E
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLV7
343
40764
A144
E
E
E
E
E
Y
V
A
D
K
E
D
L
P
K
Zebra Danio
Brachydanio rerio
Q568K9
341
40523
E142
E
E
E
E
E
E
E
E
D
E
I
E
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAY7
359
42838
K153
Q
E
D
Q
P
K
P
K
W
T
E
I
K
E
D
Honey Bee
Apis mellifera
XP_624083
345
40901
K137
F
L
E
G
E
T
E
K
S
E
I
L
K
D
N
Nematode Worm
Caenorhab. elegans
Q18691
326
37886
D123
F
L
S
F
A
F
D
D
E
E
D
E
E
D
A
Sea Urchin
Strong. purpuratus
XP_001183761
318
37639
K131
D
G
D
A
V
V
K
K
K
K
R
I
G
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H110
337
39221
D136
E
N
G
S
D
E
D
D
G
E
N
K
S
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
99.7
N.A.
N.A.
98.2
98.5
N.A.
84.6
N.A.
87.4
86.2
N.A.
62.6
62.6
45.4
66.6
Protein Similarity:
100
74.7
99.7
N.A.
N.A.
99.4
99.7
N.A.
87
N.A.
92.7
94.1
N.A.
79.9
79.7
66
82.6
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
86.6
86.6
N.A.
66.6
N.A.
33.3
40
N.A.
13.3
13.3
26.6
0
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
80
N.A.
60
46.6
N.A.
53.3
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
24
39
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
16
8
16
24
16
0
8
8
0
16
8
% D
% Glu:
70
70
70
62
24
16
16
8
54
77
62
16
62
16
47
% E
% Phe:
16
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
0
8
0
0
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
16
16
0
0
8
% I
% Lys:
0
0
0
0
0
8
8
24
8
16
0
8
16
8
8
% K
% Leu:
0
16
0
0
0
0
0
0
0
0
0
31
8
0
0
% L
% Met:
0
0
0
0
16
0
39
0
0
0
0
24
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
16
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
39
0
% R
% Ser:
0
0
8
8
0
0
0
0
8
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
16
8
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _