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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRG1
All Species:
20.91
Human Site:
S224
Identified Species:
38.33
UniProt:
Q14331
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14331
NP_004468.1
258
29172
S224
Q
D
H
K
L
K
I
S
K
E
D
S
K
I
L
Chimpanzee
Pan troglodytes
XP_001136401
250
28131
F216
Y
V
K
K
F
Q
S
F
Q
D
H
K
L
K
I
Rhesus Macaque
Macaca mulatta
XP_001090694
258
29090
S224
Q
D
H
K
L
K
I
S
K
E
D
S
K
I
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97376
258
29109
S224
Q
D
H
K
L
K
I
S
K
E
D
S
K
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516374
198
22206
S164
Q
D
R
K
L
K
I
S
Q
E
D
S
K
V
L
Chicken
Gallus gallus
XP_420681
256
28915
S222
Q
D
K
K
L
K
V
S
K
E
D
T
K
A
L
Frog
Xenopus laevis
NP_001086250
210
23113
K177
A
G
E
G
E
M
I
K
I
R
S
C
A
E
R
Zebra Danio
Brachydanio rerio
NP_001017793
255
28761
N221
Q
D
R
K
L
R
L
N
E
E
D
S
G
S
L
Tiger Blowfish
Takifugu rubipres
O73747
255
28711
N221
Q
D
R
R
L
R
V
N
E
G
D
S
M
T
L
Fruit Fly
Dros. melanogaster
Q9VWA8
262
29511
N228
Q
D
K
K
M
R
I
N
Q
N
D
V
K
E
L
Honey Bee
Apis mellifera
XP_625206
258
29196
S224
Q
D
K
K
L
K
I
S
K
E
D
N
S
K
L
Nematode Worm
Caenorhab. elegans
O18282
274
30250
D241
K
N
R
H
I
A
I
D
V
K
D
K
K
G
V
Sea Urchin
Strong. purpuratus
XP_001204166
254
28213
K219
E
C
E
V
S
Y
V
K
K
F
Q
S
F
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
99.2
N.A.
N.A.
97.2
N.A.
N.A.
64.3
85.6
66.6
76.7
71.7
48.4
53.8
43.4
53.4
Protein Similarity:
100
96.5
99.2
N.A.
N.A.
99.2
N.A.
N.A.
70.5
92.2
73.6
89.1
85.2
66
71.3
60.9
70.1
P-Site Identity:
100
6.6
100
N.A.
N.A.
100
N.A.
N.A.
80
73.3
6.6
53.3
40
46.6
73.3
20
13.3
P-Site Similarity:
100
33.3
100
N.A.
N.A.
100
N.A.
N.A.
93.3
86.6
6.6
80
73.3
73.3
80
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
70
0
0
0
0
0
8
0
8
77
0
0
0
8
% D
% Glu:
8
0
16
0
8
0
0
0
16
54
0
0
0
16
0
% E
% Phe:
0
0
0
0
8
0
0
8
0
8
0
0
8
0
0
% F
% Gly:
0
8
0
8
0
0
0
0
0
8
0
0
8
8
0
% G
% His:
0
0
24
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
62
0
8
0
0
0
0
24
8
% I
% Lys:
8
0
31
70
0
47
0
16
47
8
0
16
54
16
0
% K
% Leu:
0
0
0
0
62
0
8
0
0
0
0
0
8
0
70
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
24
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
70
0
0
0
0
8
0
0
24
0
8
0
0
8
0
% Q
% Arg:
0
0
31
8
0
24
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
0
0
0
8
0
8
47
0
0
8
54
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
8
0
8
0
0
24
0
8
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _