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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRG1
All Species:
27.27
Human Site:
Y113
Identified Species:
50
UniProt:
Q14331
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14331
NP_004468.1
258
29172
Y113
R
I
A
L
K
S
G
Y
G
K
Y
L
G
I
N
Chimpanzee
Pan troglodytes
XP_001136401
250
28131
Y113
R
I
A
L
K
S
G
Y
G
K
Y
L
G
I
N
Rhesus Macaque
Macaca mulatta
XP_001090694
258
29090
Y113
R
I
A
L
K
S
G
Y
G
K
Y
L
G
I
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97376
258
29109
Y113
R
I
A
L
K
S
G
Y
G
K
Y
L
G
I
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516374
198
22206
G67
N
A
D
G
L
V
V
G
R
S
D
A
I
G
P
Chicken
Gallus gallus
XP_420681
256
28915
K113
A
L
K
S
G
Y
G
K
Y
L
G
I
N
S
D
Frog
Xenopus laevis
NP_001086250
210
23113
A80
N
G
L
F
T
I
G
A
P
H
K
D
D
D
D
Zebra Danio
Brachydanio rerio
NP_001017793
255
28761
Y113
L
K
S
G
Y
G
K
Y
L
G
I
N
S
E
G
Tiger Blowfish
Takifugu rubipres
O73747
255
28711
Y113
L
K
S
G
Y
G
R
Y
L
G
I
N
S
E
G
Fruit Fly
Dros. melanogaster
Q9VWA8
262
29511
Y117
K
V
A
F
K
S
G
Y
G
K
Y
L
K
I
E
Honey Bee
Apis mellifera
XP_625206
258
29196
Y113
K
V
A
L
K
S
G
Y
G
K
Y
L
G
V
D
Nematode Worm
Caenorhab. elegans
O18282
274
30250
F124
K
I
S
L
K
T
G
F
G
R
Y
V
G
V
D
Sea Urchin
Strong. purpuratus
XP_001204166
254
28213
Y121
K
I
A
F
K
S
G
Y
G
K
F
L
G
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
99.2
N.A.
N.A.
97.2
N.A.
N.A.
64.3
85.6
66.6
76.7
71.7
48.4
53.8
43.4
53.4
Protein Similarity:
100
96.5
99.2
N.A.
N.A.
99.2
N.A.
N.A.
70.5
92.2
73.6
89.1
85.2
66
71.3
60.9
70.1
P-Site Identity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
0
6.6
6.6
6.6
6.6
66.6
73.3
46.6
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
0
26.6
13.3
13.3
13.3
80
100
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
54
0
0
0
0
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
8
8
8
8
39
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% E
% Phe:
0
0
0
24
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
24
8
16
77
8
62
16
8
0
54
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
47
0
0
0
8
0
0
0
0
16
8
8
39
0
% I
% Lys:
31
16
8
0
62
0
8
8
0
54
8
0
8
0
0
% K
% Leu:
16
8
8
47
8
0
0
0
16
8
0
54
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
0
0
0
16
8
0
31
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
31
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
24
8
0
54
0
0
0
8
0
0
16
8
0
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
16
0
0
0
8
8
0
0
0
0
8
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
8
0
70
8
0
54
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _