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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD2
All Species:
24.55
Human Site:
T194
Identified Species:
49.09
UniProt:
Q14332
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14332
NP_001457.1
565
63554
T194
G
A
P
P
R
Y
A
T
L
E
H
P
F
H
C
Chimpanzee
Pan troglodytes
XP_519190
643
70814
S265
F
P
G
G
A
G
A
S
E
R
G
K
F
S
C
Rhesus Macaque
Macaca mulatta
XP_001101358
513
57042
Q153
A
E
Q
I
C
V
G
Q
N
H
S
E
D
G
A
Dog
Lupus familis
XP_548060
565
63582
T194
G
S
P
P
R
Y
A
T
L
E
H
P
F
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP6
570
64040
T199
G
S
P
P
R
Y
A
T
L
E
H
P
F
H
C
Rat
Rattus norvegicus
Q08464
570
63867
T199
G
A
P
P
R
Y
A
T
L
E
H
P
F
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519817
718
80521
T347
G
G
A
P
R
Y
A
T
L
D
R
P
F
H
C
Chicken
Gallus gallus
Q9IA06
523
59263
R155
P
R
Y
A
T
P
D
R
P
F
H
C
P
R
A
Frog
Xenopus laevis
Q9PUU6
551
62443
T180
P
G
P
P
I
Y
A
T
L
D
H
P
F
H
C
Zebra Danio
Brachydanio rerio
NP_571215
550
61730
T178
P
S
V
Q
L
Y
S
T
P
D
K
P
F
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
H198
Q
T
G
V
E
S
P
H
R
N
I
G
F
V
C
Honey Bee
Apis mellifera
XP_623523
571
64519
A188
G
S
G
F
M
L
G
A
R
D
F
G
F
V
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
84.7
99.6
N.A.
98.7
97
N.A.
75
84.7
87.7
76.2
N.A.
45.9
56
N.A.
N.A.
Protein Similarity:
100
77.9
86.9
99.8
N.A.
98.9
97
N.A.
76.4
88.1
91.5
84.4
N.A.
61.2
70.7
N.A.
N.A.
P-Site Identity:
100
20
0
93.3
N.A.
93.3
100
N.A.
73.3
6.6
73.3
33.3
N.A.
13.3
20
N.A.
N.A.
P-Site Similarity:
100
26.6
0
100
N.A.
100
100
N.A.
80
6.6
80
53.3
N.A.
13.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
9
9
0
59
9
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
84
% C
% Asp:
0
0
0
0
0
0
9
0
0
34
0
0
9
0
0
% D
% Glu:
0
9
0
0
9
0
0
0
9
34
0
9
0
0
0
% E
% Phe:
9
0
0
9
0
0
0
0
0
9
9
0
84
0
0
% F
% Gly:
50
17
25
9
0
9
17
0
0
0
9
17
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
9
50
0
0
50
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% K
% Leu:
0
0
0
0
9
9
0
0
50
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
25
9
42
50
0
9
9
0
17
0
0
59
9
0
0
% P
% Gln:
9
0
9
9
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
42
0
0
9
17
9
9
0
0
17
0
% R
% Ser:
0
34
0
0
0
9
9
9
0
0
9
0
0
9
0
% S
% Thr:
0
9
0
0
9
0
0
59
0
0
0
0
0
0
0
% T
% Val:
0
0
9
9
0
9
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
59
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _