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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GALE All Species: 47.88
Human Site: S132 Identified Species: 87.78
UniProt: Q14376 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14376 NP_000394.2 348 38282 S132 K N L V F S S S A T V Y G N P
Chimpanzee Pan troglodytes XP_513199 348 38237 S132 K N L V F S S S A T V Y G N P
Rhesus Macaque Macaca mulatta XP_001104086 348 38147 S132 K N L V F S S S A T V Y G N P
Dog Lupus familis XP_544499 348 38232 S132 K N L V F S S S A T V Y G N P
Cat Felis silvestris
Mouse Mus musculus Q8R059 347 38206 S131 K N L V F S S S A T V Y G N P
Rat Rattus norvegicus P18645 347 38206 S131 V K S L V F S S S A T V Y G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417833 347 38279 S132 R N I V F S S S A T V Y G D P
Frog Xenopus laevis NP_001080902 348 38239 S132 K N I V F S S S A T V Y G D P
Zebra Danio Brachydanio rerio NP_001035389 349 38819 S131 R N L V F S S S A T V Y G D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0P5 350 38678 S133 F K F V Y S S S A T V Y G E P
Honey Bee Apis mellifera XP_395102 353 39716 S136 K C F I Y S S S A T V Y G I P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SN58 351 38599 S130 K N L V F S S S A T V Y G S P
Baker's Yeast Sacchar. cerevisiae P04397 699 78177 S135 S K F V F S S S A T V Y G D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.6 93.3 N.A. 93.6 87 N.A. N.A. 75 75.5 73 N.A. 60 58 N.A. N.A.
Protein Similarity: 100 100 98.8 96.8 N.A. 95.4 89.9 N.A. N.A. 87.6 87.9 85.9 N.A. 75.7 76.7 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 80 86.6 86.6 N.A. 66.6 66.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. 100 100 100 N.A. 73.3 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 58.4 28 N.A.
Protein Similarity: N.A. N.A. N.A. 72 37.2 N.A.
P-Site Identity: N.A. N.A. N.A. 93.3 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 100 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 93 8 0 0 0 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 8 0 24 0 77 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 93 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 8 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 62 24 0 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 54 8 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 70 0 0 0 0 0 0 0 0 0 0 0 39 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 8 0 0 93 100 100 8 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 93 8 0 0 0 0 % T
% Val: 8 0 0 85 8 0 0 0 0 0 93 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 16 0 0 0 0 0 0 93 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _