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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GGTLC2 All Species: 23.94
Human Site: Y30 Identified Species: 58.52
UniProt: Q14390 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14390 NP_954578 218 23661 Y30 S Y Y K P E F Y T P V D G G T
Chimpanzee Pan troglodytes XP_001170956 562 60871 Y374 S Y Y K P E F Y T P D D G G T
Rhesus Macaque Macaca mulatta XP_001093430 562 60732 Y374 S Y Y K P E F Y T P D D G G T
Dog Lupus familis XP_543526 569 61179 Y374 S Y Y E P E F Y T P D D G G T
Cat Felis silvestris
Mouse Mus musculus Q60928 568 61544 Y373 A Y Y E P E F Y L Q D D G G T
Rat Rattus norvegicus P07314 568 61591 Y373 A Y Y E P E F Y L P D D G G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517861 229 24651 Y34 D Y Y E P E Y Y T P D N A G T
Chicken Gallus gallus
Frog Xenopus laevis NP_001089832 573 62607 F377 D Y Y E P T Y F I Q D P H G T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393584 575 62805 V380 T Y Y G A I T V P P D D S G T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785511 229 25186 Q34 T Y Y E P E F Q L V E D S G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.7 36.6 31.8 N.A. 30.1 31.1 N.A. 68.1 N.A. 24.7 N.A. N.A. N.A. 20 N.A. 43.6
Protein Similarity: 100 38.4 37.7 34.6 N.A. 33.6 34.3 N.A. 78.5 N.A. 30.3 N.A. N.A. N.A. 27.2 N.A. 62
P-Site Identity: 100 93.3 93.3 86.6 N.A. 66.6 73.3 N.A. 60 N.A. 33.3 N.A. N.A. N.A. 40 N.A. 53.3
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 80 86.6 N.A. 80 N.A. 53.3 N.A. N.A. N.A. 46.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 0 0 0 0 0 0 80 80 0 0 0 % D
% Glu: 0 0 0 60 0 80 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 70 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 60 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 90 0 0 0 10 70 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 20 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 40 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % S
% Thr: 20 0 0 0 0 10 10 0 50 0 0 0 0 0 100 % T
% Val: 0 0 0 0 0 0 0 10 0 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 100 100 0 0 0 20 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _