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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCKR
All Species:
13.64
Human Site:
S264
Identified Species:
37.5
UniProt:
Q14397
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14397
NP_001477.2
625
68701
S264
S
S
R
M
K
G
G
S
A
T
K
I
L
L
E
Chimpanzee
Pan troglodytes
XP_515364
625
68806
S264
S
S
R
M
K
G
G
S
A
T
K
I
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001098190
625
68633
S264
S
S
R
M
K
G
G
S
A
T
K
I
L
L
E
Dog
Lupus familis
XP_532912
624
68750
S263
S
S
R
M
K
G
G
S
A
T
K
I
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91X44
587
64661
M233
F
R
Q
V
A
E
R
M
Q
K
M
Q
E
K
Q
Rat
Rattus norvegicus
Q07071
627
68899
G264
S
S
R
M
K
G
G
G
A
T
K
I
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91754
619
68720
G263
G
S
S
R
M
K
G
G
S
A
T
K
I
L
L
Zebra Danio
Brachydanio rerio
XP_002665191
556
62637
I211
K
G
G
S
A
T
K
I
I
L
E
T
L
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198229
583
63447
A231
N
P
I
V
G
P
E
A
I
T
G
S
S
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.9
90.8
N.A.
82.2
88
N.A.
N.A.
N.A.
57.9
40
N.A.
N.A.
N.A.
N.A.
32.1
Protein Similarity:
100
99
98.4
95
N.A.
88.3
93.7
N.A.
N.A.
N.A.
78.2
59.6
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
100
100
N.A.
0
93.3
N.A.
N.A.
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
0
0
12
56
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
12
0
0
0
12
0
12
0
56
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
12
0
12
56
67
23
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
12
23
0
0
56
12
0
0
% I
% Lys:
12
0
0
0
56
12
12
0
0
12
56
12
0
12
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
0
67
78
12
% L
% Met:
0
0
0
56
12
0
0
12
0
0
12
0
0
0
23
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
12
0
0
12
0
0
12
% Q
% Arg:
0
12
56
12
0
0
12
0
0
0
0
0
0
12
0
% R
% Ser:
56
67
12
12
0
0
0
45
12
0
0
12
12
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
67
12
12
0
0
0
% T
% Val:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _