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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCKR
All Species:
11.52
Human Site:
S319
Identified Species:
31.67
UniProt:
Q14397
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14397
NP_001477.2
625
68701
S319
K
I
A
T
L
M
K
S
V
S
T
S
L
E
K
Chimpanzee
Pan troglodytes
XP_515364
625
68806
S319
K
I
A
A
L
M
K
S
V
S
T
S
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001098190
625
68633
S319
K
I
A
T
L
M
K
S
V
S
T
S
L
E
K
Dog
Lupus familis
XP_532912
624
68750
Q318
K
I
A
A
L
M
K
Q
A
S
S
S
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91X44
587
64661
S288
V
D
Q
G
V
V
S
S
Q
R
C
L
L
E
I
Rat
Rattus norvegicus
Q07071
627
68899
Q319
K
I
A
T
L
M
K
Q
V
G
I
S
L
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91754
619
68720
Q318
K
I
A
A
L
M
K
Q
T
A
T
S
L
Q
K
Zebra Danio
Brachydanio rerio
XP_002665191
556
62637
S266
L
I
Q
K
A
G
E
S
L
Q
M
K
A
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198229
583
63447
K286
N
D
S
S
K
Q
E
K
L
I
T
S
L
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.9
90.8
N.A.
82.2
88
N.A.
N.A.
N.A.
57.9
40
N.A.
N.A.
N.A.
N.A.
32.1
Protein Similarity:
100
99
98.4
95
N.A.
88.3
93.7
N.A.
N.A.
N.A.
78.2
59.6
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
93.3
100
73.3
N.A.
20
80
N.A.
N.A.
N.A.
66.6
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
100
80
N.A.
33.3
80
N.A.
N.A.
N.A.
80
26.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
34
12
0
0
0
12
12
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
23
0
0
0
0
0
0
67
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
12
0
12
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
78
0
0
0
0
0
0
0
12
12
0
0
0
12
% I
% Lys:
67
0
0
12
12
0
67
12
0
0
0
12
0
0
67
% K
% Leu:
12
0
0
0
67
0
0
0
23
0
0
12
89
0
0
% L
% Met:
0
0
0
0
0
67
0
0
0
0
12
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
23
0
0
12
0
34
12
12
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
12
12
0
0
12
56
0
45
12
78
0
0
0
% S
% Thr:
0
0
0
34
0
0
0
0
12
0
56
0
0
0
0
% T
% Val:
12
0
0
0
12
12
0
0
45
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _