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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCKR
All Species:
25.15
Human Site:
S549
Identified Species:
69.17
UniProt:
Q14397
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14397
NP_001477.2
625
68701
S549
I
H
F
P
Q
P
L
S
D
D
I
R
A
A
P
Chimpanzee
Pan troglodytes
XP_515364
625
68806
S549
I
H
F
P
Q
P
L
S
D
D
I
R
A
A
P
Rhesus Macaque
Macaca mulatta
XP_001098190
625
68633
S549
I
H
F
P
Q
P
L
S
D
D
I
R
A
A
P
Dog
Lupus familis
XP_532912
624
68750
S548
I
H
F
P
Q
P
L
S
D
D
I
R
A
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91X44
587
64661
S513
I
H
F
P
Q
P
L
S
N
D
V
R
A
A
P
Rat
Rattus norvegicus
Q07071
627
68899
S549
I
H
F
P
Q
P
L
S
D
D
V
R
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91754
619
68720
S548
I
Y
G
E
Q
T
L
S
E
Q
I
R
N
T
T
Zebra Danio
Brachydanio rerio
XP_002665191
556
62637
L489
V
I
Y
N
T
D
D
L
T
E
E
T
R
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198229
583
63447
R516
A
V
M
R
A
I
Y
R
T
D
D
I
A
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.9
90.8
N.A.
82.2
88
N.A.
N.A.
N.A.
57.9
40
N.A.
N.A.
N.A.
N.A.
32.1
Protein Similarity:
100
99
98.4
95
N.A.
88.3
93.7
N.A.
N.A.
N.A.
78.2
59.6
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
N.A.
40
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
53.3
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
0
0
78
56
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
0
56
78
12
0
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
0
12
12
12
0
0
0
0
% E
% Phe:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
78
12
0
0
0
12
0
0
0
0
56
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
78
12
0
0
0
0
0
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
12
0
0
0
12
0
0
% N
% Pro:
0
0
0
67
0
67
0
0
0
0
0
0
0
0
67
% P
% Gln:
0
0
0
0
78
0
0
0
0
12
0
0
0
12
0
% Q
% Arg:
0
0
0
12
0
0
0
12
0
0
0
78
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
78
0
0
0
0
0
23
0
% S
% Thr:
0
0
0
0
12
12
0
0
23
0
0
12
0
12
12
% T
% Val:
12
12
0
0
0
0
0
0
0
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _