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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCKR
All Species:
21.82
Human Site:
T352
Identified Species:
60
UniProt:
Q14397
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14397
NP_001477.2
625
68701
T352
D
G
V
E
C
I
H
T
F
G
A
D
F
R
D
Chimpanzee
Pan troglodytes
XP_515364
625
68806
T352
D
G
V
E
C
I
H
T
F
G
A
D
F
R
D
Rhesus Macaque
Macaca mulatta
XP_001098190
625
68633
T352
D
G
V
E
C
I
H
T
F
G
A
D
F
R
D
Dog
Lupus familis
XP_532912
624
68750
T351
D
G
V
E
C
I
H
T
F
G
A
D
F
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91X44
587
64661
G321
A
T
L
T
K
Q
V
G
I
S
L
E
K
K
G
Rat
Rattus norvegicus
Q07071
627
68899
T352
D
G
V
E
C
I
H
T
F
G
A
D
F
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91754
619
68720
T351
D
A
V
E
C
V
P
T
Y
Q
A
D
W
R
D
Zebra Danio
Brachydanio rerio
XP_002665191
556
62637
D299
C
M
P
T
F
G
A
D
F
G
D
I
R
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198229
583
63447
K319
K
L
I
E
Q
A
G
K
R
G
F
L
K
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.9
90.8
N.A.
82.2
88
N.A.
N.A.
N.A.
57.9
40
N.A.
N.A.
N.A.
N.A.
32.1
Protein Similarity:
100
99
98.4
95
N.A.
88.3
93.7
N.A.
N.A.
N.A.
78.2
59.6
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
100
93.3
N.A.
0
93.3
N.A.
N.A.
N.A.
60
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
N.A.
N.A.
80
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
12
12
0
0
0
67
0
0
0
0
% A
% Cys:
12
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
0
0
0
12
0
0
12
67
0
0
67
% D
% Glu:
0
0
0
78
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
67
0
12
0
56
0
12
% F
% Gly:
0
56
0
0
0
12
12
12
0
78
0
0
0
23
23
% G
% His:
0
0
0
0
0
0
56
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
56
0
0
12
0
0
12
0
0
0
% I
% Lys:
12
0
0
0
12
0
0
12
0
0
0
0
23
12
0
% K
% Leu:
0
12
12
0
0
0
0
0
0
0
12
12
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
12
0
0
0
12
0
0
0
23
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
12
45
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% S
% Thr:
0
12
0
23
0
0
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
67
0
0
12
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _