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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCKR
All Species:
24.55
Human Site:
Y24
Identified Species:
67.5
UniProt:
Q14397
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14397
NP_001477.2
625
68701
Y24
G
K
W
E
L
S
G
Y
E
A
A
V
P
I
T
Chimpanzee
Pan troglodytes
XP_515364
625
68806
Y24
G
K
W
E
L
S
G
Y
E
A
A
V
P
I
T
Rhesus Macaque
Macaca mulatta
XP_001098190
625
68633
Y24
G
K
W
E
L
S
G
Y
E
A
A
V
P
I
T
Dog
Lupus familis
XP_532912
624
68750
T30
Y
E
A
A
L
P
I
T
E
K
S
N
P
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91X44
587
64661
Y24
G
E
W
E
L
S
G
Y
E
A
A
V
P
I
T
Rat
Rattus norvegicus
Q07071
627
68899
Y24
G
E
W
E
L
S
G
Y
E
A
A
V
P
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91754
619
68720
Y24
G
K
W
E
L
A
G
Y
E
E
S
L
P
I
S
Zebra Danio
Brachydanio rerio
XP_002665191
556
62637
N19
L
P
V
T
E
K
S
N
P
I
S
R
G
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198229
583
63447
K24
V
T
E
L
S
N
R
K
S
E
N
I
D
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.9
90.8
N.A.
82.2
88
N.A.
N.A.
N.A.
57.9
40
N.A.
N.A.
N.A.
N.A.
32.1
Protein Similarity:
100
99
98.4
95
N.A.
88.3
93.7
N.A.
N.A.
N.A.
78.2
59.6
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
66.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
46.6
N.A.
100
100
N.A.
N.A.
N.A.
93.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
12
0
0
0
56
56
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
0
34
12
67
12
0
0
0
78
23
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
67
0
0
0
0
0
67
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
12
0
12
0
78
0
% I
% Lys:
0
45
0
0
0
12
0
12
0
12
0
0
0
0
0
% K
% Leu:
12
0
0
12
78
0
0
0
0
0
0
12
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
12
12
0
0
0
% N
% Pro:
0
12
0
0
0
12
0
0
12
0
0
0
78
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
12
56
12
0
12
0
34
0
0
0
12
% S
% Thr:
0
12
0
12
0
0
0
12
0
0
0
0
0
12
67
% T
% Val:
12
0
12
0
0
0
0
0
0
0
0
56
0
0
0
% V
% Trp:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _