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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GK3P All Species: 19.39
Human Site: S525 Identified Species: 42.67
UniProt: Q14409 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14409 NP_001121599 553 60598 S525 S P E G G D P S V F C S L P L
Chimpanzee Pan troglodytes XP_001150384 553 60623 S525 S P E G G D P S V F C S L P L
Rhesus Macaque Macaca mulatta XP_001100968 553 60557 S525 S P E S G D P S I F C S L P L
Dog Lupus familis XP_860266 553 60656 S525 S S E S G D P S I F C S L P L
Cat Felis silvestris
Mouse Mus musculus Q64516 559 61209 S531 S P E S G D P S I F C S L P L
Rat Rattus norvegicus Q63060 524 57458 S496 P Q I N A E E S E I R Y S T W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506589 596 65239 E560 A V T M E R F E P Q I N E E E
Chicken Gallus gallus XP_416788 520 57169 S491 P Q I N P E E S E Y R Y A R W
Frog Xenopus laevis NP_001080640 563 61588 D532 P T S N G N G D C S I F C S L
Zebra Danio Brachydanio rerio NP_001108056 530 58172 L500 I N P E E S E L R Y A R W K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21944 502 55146 T475 S S E D N R Y T P Q K D D N W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96.9 95.8 N.A. 94.9 91.3 N.A. 77 79.7 82.4 76.1 N.A. N.A. N.A. 47 N.A.
Protein Similarity: 100 99.8 98.7 97.8 N.A. 97.5 93.3 N.A. 83.2 86.9 89.6 84.9 N.A. N.A. N.A. 63.6 N.A.
P-Site Identity: 100 100 86.6 80 N.A. 86.6 6.6 N.A. 0 6.6 13.3 0 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 13.3 N.A. 13.3 20 20 6.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 46 0 10 0 0 % C
% Asp: 0 0 0 10 0 46 0 10 0 0 0 10 10 0 0 % D
% Glu: 0 0 55 10 19 19 28 10 19 0 0 0 10 10 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 46 0 10 0 0 0 % F
% Gly: 0 0 0 19 55 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 19 0 0 0 0 0 28 10 19 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 0 0 46 0 55 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 28 10 10 0 0 0 0 0 10 0 10 0 % N
% Pro: 28 37 10 0 10 0 46 0 19 0 0 0 0 46 0 % P
% Gln: 0 19 0 0 0 0 0 0 0 19 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 19 0 0 10 0 19 10 0 10 0 % R
% Ser: 55 19 10 28 0 10 0 64 0 10 0 46 10 10 0 % S
% Thr: 0 10 10 0 0 0 0 10 0 0 0 0 0 10 0 % T
% Val: 0 10 0 0 0 0 0 0 19 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 28 % W
% Tyr: 0 0 0 0 0 0 10 0 0 19 0 19 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _