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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GK2
All Species:
21.82
Human Site:
Y500
Identified Species:
48
UniProt:
Q14410
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14410
NP_149991.2
553
60594
Y500
A
T
E
S
E
I
R
Y
A
T
W
K
K
A
V
Chimpanzee
Pan troglodytes
XP_526574
918
101889
Y500
A
T
E
S
E
I
R
Y
A
T
W
K
K
A
V
Rhesus Macaque
Macaca mulatta
XP_001090807
553
60686
Y500
A
T
E
S
E
I
R
Y
A
T
W
K
K
A
V
Dog
Lupus familis
XP_860266
553
60656
Y500
A
E
E
S
E
I
R
Y
S
T
W
K
K
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q64516
559
61209
Y506
A
E
E
S
E
I
R
Y
S
T
W
K
K
A
V
Rat
Rattus norvegicus
Q63060
524
57458
V471
G
A
A
E
G
V
G
V
W
S
L
E
P
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506589
596
65239
S537
G
A
A
M
A
A
G
S
A
E
G
V
A
V
W
Chicken
Gallus gallus
XP_416788
520
57169
S468
A
E
G
V
G
I
W
S
L
N
P
G
D
L
T
Frog
Xenopus laevis
NP_001080640
563
61588
Y507
P
E
E
S
E
F
R
Y
A
R
W
K
K
A
V
Zebra Danio
Brachydanio rerio
NP_001108056
530
58172
P478
V
S
V
W
S
L
N
P
E
D
L
T
E
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21944
502
55146
G447
I
T
E
I
S
G
W
G
A
A
V
A
G
G
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
98
88.7
N.A.
87.1
83.3
N.A.
73.6
74.6
77.8
72.3
N.A.
N.A.
N.A.
44.4
N.A.
Protein Similarity:
100
60
99.6
95.1
N.A.
94.2
90
N.A.
81.7
85.3
87.9
83.9
N.A.
N.A.
N.A.
63.2
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
6.6
13.3
73.3
0
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
6.6
13.3
73.3
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
19
19
0
10
10
0
0
55
10
0
10
10
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% D
% Glu:
0
37
64
10
55
0
0
0
10
10
0
10
10
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
10
0
19
10
19
10
0
0
10
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
55
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
55
55
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
19
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
55
0
0
10
0
0
0
0
0
% R
% Ser:
0
10
0
55
19
0
0
19
19
10
0
0
0
0
0
% S
% Thr:
0
37
0
0
0
0
0
0
0
46
0
10
0
0
19
% T
% Val:
10
0
10
10
0
10
0
10
0
0
10
10
0
19
55
% V
% Trp:
0
0
0
10
0
0
19
0
10
0
55
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _