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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM2 All Species: 14.85
Human Site: S282 Identified Species: 27.22
UniProt: Q14416 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14416 NP_000830.2 872 95568 S282 A R E L L A A S Q R L N A S F
Chimpanzee Pan troglodytes A3QNZ8 839 95029 Q247 L P A L Q P N Q N M T S E E R
Rhesus Macaque Macaca mulatta A3QP01 839 95041 T239 I C I A F Q E T L P T V Q P N
Dog Lupus familis XP_541867 872 95696 T282 A R E L L A A T Q R L N A S F
Cat Felis silvestris
Mouse Mus musculus Q14BI2 872 95869 T282 A R E L L A A T Q R L N A S F
Rat Rattus norvegicus P31421 872 95755 T282 A R E L L A A T Q R L N A S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518731 870 95758 A282 A R E L L A A A Q R L N A S F
Chicken Gallus gallus XP_416842 879 98936 A288 S R E L I A A A N R F N V S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 S283 V I S F A K S S Q M Q L L F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 R297 R I L Q A A K R A N L S Q P F
Honey Bee Apis mellifera NP_001011624 933 103448 R308 G I L E A A R R S N L S Q P F
Nematode Worm Caenorhab. elegans Q09630 999 113258 G352 E R M K L T S G A K K R I I W
Sea Urchin Strong. purpuratus XP_784936 1474 165598 R858 D L L E A A L R V N A S K K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.6 27.6 98.1 N.A. 97.4 97.8 N.A. 88.3 67.9 N.A. 25.5 N.A. 45.7 47 39.9 32.2
Protein Similarity: 100 46.3 46.3 98.9 N.A. 98.5 98.7 N.A. 92.7 82.2 N.A. 43.8 N.A. 61.7 63.3 55.6 43.4
P-Site Identity: 100 6.6 0 93.3 N.A. 93.3 93.3 N.A. 93.3 60 N.A. 13.3 N.A. 20 20 13.3 13.3
P-Site Similarity: 100 13.3 6.6 100 N.A. 100 100 N.A. 100 80 N.A. 20 N.A. 26.6 26.6 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 8 8 31 70 47 16 16 0 8 0 39 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 47 16 0 0 8 0 0 0 0 0 8 8 0 % E
% Phe: 0 0 0 8 8 0 0 0 0 0 8 0 0 8 70 % F
% Gly: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 24 8 0 8 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 0 0 0 8 0 8 8 0 0 8 8 0 8 8 8 % K
% Leu: 8 8 24 54 47 0 8 0 8 0 54 8 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 16 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 16 24 0 47 0 0 8 % N
% Pro: 0 8 0 0 0 8 0 0 0 8 0 0 0 24 0 % P
% Gln: 0 0 0 8 8 8 0 8 47 0 8 0 24 0 0 % Q
% Arg: 8 54 0 0 0 0 8 24 0 47 0 8 0 0 8 % R
% Ser: 8 0 8 0 0 0 16 16 8 0 0 31 0 47 0 % S
% Thr: 0 0 0 0 0 8 0 31 0 0 16 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 8 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _