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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM2 All Species: 21.21
Human Site: S366 Identified Species: 38.89
UniProt: Q14416 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14416 NP_000830.2 872 95568 S366 Q R D C A A H S L R A V P F E
Chimpanzee Pan troglodytes A3QNZ8 839 95029 P331 G I T I Q S V P I P G F S E F
Rhesus Macaque Macaca mulatta A3QP01 839 95041 T326 M G T F L G I T I Q S V P I P
Dog Lupus familis XP_541867 872 95696 S366 R R D C A A H S L Q A V P F E
Cat Felis silvestris
Mouse Mus musculus Q14BI2 872 95869 S366 Q R D C A A H S L R A V P F E
Rat Rattus norvegicus P31421 872 95755 S366 Q R D C A A H S L R A V P F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518731 870 95758 S366 Q R D C G S H S L W A V P F E
Chicken Gallus gallus XP_416842 879 98936 T378 K T C D K H F T I N S S N Y E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 L366 F L K E F L K L N A G N A S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 L406 E C D D S Y R L S E K V G Y E
Honey Bee Apis mellifera NP_001011624 933 103448 L408 F C P P N L R L T S E R G Y E
Nematode Worm Caenorhab. elegans Q09630 999 113258 K444 A S R C E D I K Q S T E G F N
Sea Urchin Strong. purpuratus XP_784936 1474 165598 V949 S T P C A E N V L D E A N H A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.6 27.6 98.1 N.A. 97.4 97.8 N.A. 88.3 67.9 N.A. 25.5 N.A. 45.7 47 39.9 32.2
Protein Similarity: 100 46.3 46.3 98.9 N.A. 98.5 98.7 N.A. 92.7 82.2 N.A. 43.8 N.A. 61.7 63.3 55.6 43.4
P-Site Identity: 100 0 13.3 86.6 N.A. 100 100 N.A. 80 6.6 N.A. 0 N.A. 20 6.6 13.3 20
P-Site Similarity: 100 13.3 40 100 N.A. 100 100 N.A. 86.6 40 N.A. 0 N.A. 40 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 39 31 0 0 0 8 39 8 8 0 8 % A
% Cys: 0 16 8 54 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 47 16 0 8 0 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 8 8 8 0 0 0 8 16 8 0 8 62 % E
% Phe: 16 0 0 8 8 0 8 0 0 0 0 8 0 47 8 % F
% Gly: 8 8 0 0 8 8 0 0 0 0 16 0 24 0 0 % G
% His: 0 0 0 0 0 8 39 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 8 0 0 16 0 24 0 0 0 0 8 0 % I
% Lys: 8 0 8 0 8 0 8 8 0 0 8 0 0 0 0 % K
% Leu: 0 8 0 0 8 16 0 24 47 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 8 0 8 8 0 8 16 0 16 % N
% Pro: 0 0 16 8 0 0 0 8 0 8 0 0 47 0 8 % P
% Gln: 31 0 0 0 8 0 0 0 8 16 0 0 0 0 0 % Q
% Arg: 8 39 8 0 0 0 16 0 0 24 0 8 0 0 0 % R
% Ser: 8 8 0 0 8 16 0 39 8 16 16 8 8 8 0 % S
% Thr: 0 16 16 0 0 0 0 16 8 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 8 0 0 0 54 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 24 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _