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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM2 All Species: 13.94
Human Site: S843 Identified Species: 25.56
UniProt: Q14416 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14416 NP_000830.2 872 95568 S843 G S A A A R A S S S L G Q G S
Chimpanzee Pan troglodytes A3QNZ8 839 95029 L805 L N L L A I S L G Y F G P K C
Rhesus Macaque Macaca mulatta A3QP01 839 95041 L805 L N L L A I S L G Y F G P K C
Dog Lupus familis XP_541867 872 95696 S843 S S A A T R A S S S L G Q G S
Cat Felis silvestris
Mouse Mus musculus Q14BI2 872 95869 S843 G S A A P R A S A N L G Q G S
Rat Rattus norvegicus P31421 872 95755 S843 G S A A P R A S A N L G Q G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518731 870 95758 G841 R F S V T A A G S S L S H G S
Chicken Gallus gallus XP_416842 879 98936 G850 R F S V S G T G T T Y S Q S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 A833 Y E Y A R K S A E N I K G L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 T905 A V A Q G A P T S S G Y S R T
Honey Bee Apis mellifera NP_001011624 933 103448 E894 T G C E L T S E S M P L Q S A
Nematode Worm Caenorhab. elegans Q09630 999 113258 A960 N C S S R L C A N S I D E P N
Sea Urchin Strong. purpuratus XP_784936 1474 165598 E1431 D G T R F R D E V N N H N L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.6 27.6 98.1 N.A. 97.4 97.8 N.A. 88.3 67.9 N.A. 25.5 N.A. 45.7 47 39.9 32.2
Protein Similarity: 100 46.3 46.3 98.9 N.A. 98.5 98.7 N.A. 92.7 82.2 N.A. 43.8 N.A. 61.7 63.3 55.6 43.4
P-Site Identity: 100 13.3 13.3 86.6 N.A. 80 80 N.A. 40 13.3 N.A. 6.6 N.A. 20 13.3 6.6 6.6
P-Site Similarity: 100 26.6 26.6 86.6 N.A. 93.3 93.3 N.A. 46.6 40 N.A. 46.6 N.A. 33.3 26.6 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 39 39 24 16 39 16 16 0 0 0 0 0 8 % A
% Cys: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 16 % C
% Asp: 8 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 8 0 8 0 0 0 16 8 0 0 0 8 0 0 % E
% Phe: 0 16 0 0 8 0 0 0 0 0 16 0 0 0 0 % F
% Gly: 24 16 0 0 8 8 0 16 16 0 8 47 8 39 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 8 0 16 0 % K
% Leu: 16 0 16 16 8 8 0 16 0 0 39 8 0 16 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 16 0 0 0 0 0 0 8 31 8 0 8 0 8 % N
% Pro: 0 0 0 0 16 0 8 0 0 0 8 0 16 8 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 47 0 0 % Q
% Arg: 16 0 0 8 16 39 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 31 24 8 8 0 31 31 39 39 0 16 8 16 47 % S
% Thr: 8 0 8 0 16 8 8 8 8 8 0 0 0 0 16 % T
% Val: 0 8 0 16 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 16 8 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _