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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM2 All Species: 29.7
Human Site: S91 Identified Species: 54.44
UniProt: Q14416 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14416 NP_000830.2 872 95568 S91 L G A H I L D S C S K D T H A
Chimpanzee Pan troglodytes A3QNZ8 839 95029 N52 M K G I V H L N F L Q V P M C
Rhesus Macaque Macaca mulatta A3QP01 839 95041 I48 L H A N M K G I V H L D Y L Q
Dog Lupus familis XP_541867 872 95696 S91 L G A H I L D S C S K D T H A
Cat Felis silvestris
Mouse Mus musculus Q14BI2 872 95869 S91 L G A H I L D S C S K D T H A
Rat Rattus norvegicus P31421 872 95755 S91 L G A H I L D S C S K D T H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518731 870 95758 T91 L G A H I L D T C S K D T Y A
Chicken Gallus gallus XP_416842 879 98936 D97 K L G V H I L D T C S R D T Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 L96 K S P M L S S L N I T L G Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 T103 I G V H I L D T C S R D T Y A
Honey Bee Apis mellifera NP_001011624 933 103448 T114 I G V H I L D T C G R D T Y A
Nematode Worm Caenorhab. elegans Q09630 999 113258 S147 L G A L I L D S C S N P A Y A
Sea Urchin Strong. purpuratus XP_784936 1474 165598 L665 G I R L G A S L R D T C S I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.6 27.6 98.1 N.A. 97.4 97.8 N.A. 88.3 67.9 N.A. 25.5 N.A. 45.7 47 39.9 32.2
Protein Similarity: 100 46.3 46.3 98.9 N.A. 98.5 98.7 N.A. 92.7 82.2 N.A. 43.8 N.A. 61.7 63.3 55.6 43.4
P-Site Identity: 100 0 20 100 N.A. 100 100 N.A. 86.6 0 N.A. 0 N.A. 66.6 60 66.6 0
P-Site Similarity: 100 26.6 33.3 100 N.A. 100 100 N.A. 100 6.6 N.A. 13.3 N.A. 93.3 86.6 73.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 54 0 0 8 0 0 0 0 0 0 8 0 62 % A
% Cys: 0 0 0 0 0 0 0 0 62 8 0 8 0 0 8 % C
% Asp: 0 0 0 0 0 0 62 8 0 8 0 62 8 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 62 16 0 8 0 8 0 0 8 0 0 8 0 0 % G
% His: 0 8 0 54 8 8 0 0 0 8 0 0 0 31 0 % H
% Ile: 16 8 0 8 62 8 0 8 0 8 0 0 0 8 0 % I
% Lys: 16 8 0 0 0 8 0 0 0 0 39 0 0 0 0 % K
% Leu: 54 8 0 16 8 62 16 16 0 8 8 8 0 8 0 % L
% Met: 8 0 0 8 8 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 8 0 0 0 8 8 0 8 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 8 0 0 0 0 0 8 0 16 8 0 0 8 % R
% Ser: 0 8 0 0 0 8 16 39 0 54 8 0 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 24 8 0 16 0 54 8 0 % T
% Val: 0 0 16 8 8 0 0 0 8 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 39 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _