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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
24.85
Human Site:
T857
Identified Species:
45.56
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
T857
S
G
S
Q
F
V
P
T
V
C
N
G
R
E
V
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
P819
C
Y
M
I
L
F
Y
P
E
R
N
T
S
A
Y
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
P819
C
Y
M
I
L
F
Y
P
E
R
N
T
P
A
Y
Dog
Lupus familis
XP_541867
872
95696
T857
S
G
S
Q
F
V
P
T
V
C
N
G
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
T857
S
G
S
Q
L
V
P
T
V
C
N
G
R
E
V
Rat
Rattus norvegicus
P31421
872
95755
T857
S
G
S
Q
F
V
P
T
V
C
N
G
R
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
T855
S
G
S
Q
F
V
P
T
V
C
N
G
R
E
V
Chicken
Gallus gallus
XP_416842
879
98936
T864
S
A
S
M
Y
V
P
T
V
C
N
G
R
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
K847
T
G
T
E
P
Q
F
K
Q
E
N
S
V
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
A919
T
H
A
P
G
T
S
A
L
T
G
G
A
V
G
Honey Bee
Apis mellifera
NP_001011624
933
103448
T908
A
L
T
A
A
V
Q
T
S
V
G
V
T
E
I
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
T974
N
Q
Y
T
A
L
L
T
D
S
T
R
R
R
S
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
R1445
Y
N
S
G
S
V
Q
R
P
R
P
H
G
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
100
N.A.
100
80
N.A.
13.3
N.A.
6.6
20
13.3
13.3
P-Site Similarity:
100
6.6
6.6
100
N.A.
93.3
100
N.A.
100
86.6
N.A.
33.3
N.A.
26.6
40
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
16
0
0
8
0
0
0
0
8
16
0
% A
% Cys:
16
0
0
0
0
0
0
0
0
47
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
16
8
0
0
0
54
0
% E
% Phe:
0
0
0
0
31
16
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
47
0
8
8
0
0
0
0
0
16
54
8
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
0
24
8
8
0
8
0
0
0
0
0
0
% L
% Met:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
70
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
47
16
8
0
8
0
8
0
0
% P
% Gln:
0
8
0
39
0
8
16
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
24
0
8
54
8
0
% R
% Ser:
47
0
54
0
8
0
8
0
8
8
0
8
8
0
8
% S
% Thr:
16
0
16
8
0
8
0
62
0
8
8
16
8
0
8
% T
% Val:
0
0
0
0
0
62
0
0
47
8
0
8
8
8
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
16
8
0
8
0
16
0
0
0
0
0
0
8
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _