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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGH All Species: 21.82
Human Site: Y21 Identified Species: 48
UniProt: Q14442 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14442 NP_004560.1 188 21081 Y21 R L A L Q R R Y Y S P S C R E
Chimpanzee Pan troglodytes XP_001136096 204 23369 Y21 R L A L Q R R Y Y S P S C R E
Rhesus Macaque Macaca mulatta XP_001107223 188 21161 Y21 R L A L Q R R Y Y S P S C R E
Dog Lupus familis XP_854339 192 21580 Y21 R L A L Q R R Y Y S P S C R E
Cat Felis silvestris
Mouse Mus musculus Q5M9N4 188 21059 Y21 R L A L R C R Y Y S P Y C R E
Rat Rattus norvegicus NP_001102184 188 21220 Y21 R L A L R R R Y Y S P Y C R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513488 263 28251 A96 H A P A W G H A P P S G D T P
Chicken Gallus gallus XP_421190 190 21105 H21 L A L R C R Q H S A S C R E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002565 181 20430 D17 N G N W I S L D C Q T H S S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121166 191 22006 L26 V N G S K L K L I D K S V K T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177880 193 22109 D21 N L K Q G M N D D K L I C E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.1 99.4 70.8 N.A. 88.3 91.4 N.A. 45.6 70 N.A. 57.9 N.A. N.A. 25.1 N.A. 32.1
Protein Similarity: 100 58.8 99.4 77.5 N.A. 93.6 94.6 N.A. 53.2 83.6 N.A. 77.6 N.A. N.A. 42.4 N.A. 51.3
P-Site Identity: 100 100 100 100 N.A. 80 86.6 N.A. 0 6.6 N.A. 0 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 0 26.6 N.A. 0 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 55 10 0 0 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 10 0 0 10 0 0 10 64 0 0 % C
% Asp: 0 0 0 0 0 0 0 19 10 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 55 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 10 0 10 10 0 0 0 0 0 10 0 0 0 % G
% His: 10 0 0 0 0 0 10 10 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 10 0 0 10 0 0 10 % I
% Lys: 0 0 10 0 10 0 10 0 0 10 10 0 0 10 0 % K
% Leu: 10 64 10 55 0 10 10 10 0 0 10 0 0 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 19 10 10 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 10 10 55 0 0 0 10 % P
% Gln: 0 0 0 10 37 0 10 0 0 10 0 0 0 0 0 % Q
% Arg: 55 0 0 10 19 55 55 0 0 0 0 0 10 55 0 % R
% Ser: 0 0 0 10 0 10 0 0 10 55 19 46 10 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 55 0 0 19 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _