KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES1
All Species:
14.85
Human Site:
S265
Identified Species:
32.67
UniProt:
Q14469
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14469
NP_005515.1
280
29541
S265
P
N
A
V
S
P
S
S
G
P
S
L
T
A
D
Chimpanzee
Pan troglodytes
XP_001162588
239
25232
S224
P
N
A
V
S
P
S
S
G
P
S
L
T
A
D
Rhesus Macaque
Macaca mulatta
XP_001090404
221
23576
A207
A
L
P
V
A
P
R
A
G
L
Q
G
Q
G
G
Dog
Lupus familis
XP_546724
225
24255
A211
T
P
P
T
V
P
R
A
G
L
Q
N
R
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P35428
282
29730
S267
P
N
A
V
S
P
S
S
G
S
S
L
T
S
D
Rat
Rattus norvegicus
Q04666
281
29603
S266
P
N
A
V
S
P
S
S
G
S
S
L
T
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511924
287
29320
G273
P
N
A
A
S
P
S
G
A
P
S
S
V
T
A
Chicken
Gallus gallus
O57337
290
31053
G261
P
A
G
I
P
G
A
G
L
D
I
I
W
A
R
Frog
Xenopus laevis
Q6IRB2
267
28706
A245
T
N
S
N
V
G
T
A
L
P
P
S
V
S
P
Zebra Danio
Brachydanio rerio
Q8AXV5
310
33373
R238
N
P
A
L
T
S
V
R
Q
L
P
S
V
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
S359
P
P
T
S
A
E
T
S
F
N
T
S
G
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
49.2
50
N.A.
97.5
98.5
N.A.
73.5
54.1
73.5
29.3
N.A.
31.7
N.A.
N.A.
N.A.
Protein Similarity:
100
85.3
61
61.4
N.A.
97.8
98.5
N.A.
78
61.3
80.3
45.1
N.A.
41.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
13.3
N.A.
86.6
93.3
N.A.
53.3
13.3
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
20
N.A.
93.3
93.3
N.A.
53.3
33.3
40
20
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
55
10
19
0
10
28
10
0
0
0
0
37
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
37
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
19
0
19
55
0
0
10
10
19
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
10
0
0
0
0
19
28
0
37
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
55
0
10
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
64
28
19
0
10
64
0
0
0
37
19
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
19
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
19
10
0
0
0
0
10
0
10
% R
% Ser:
0
0
10
10
46
10
46
46
0
19
46
37
0
28
0
% S
% Thr:
19
0
10
10
10
0
19
0
0
0
10
0
37
10
0
% T
% Val:
0
0
0
46
19
0
10
0
0
0
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _