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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFE2L1
All Species:
19.7
Human Site:
S488
Identified Species:
43.33
UniProt:
Q14494
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14494
NP_003195.1
772
84704
S488
L
D
S
S
H
S
P
S
S
L
S
S
S
E
G
Chimpanzee
Pan troglodytes
XP_001173196
742
81481
S458
L
D
S
S
H
S
P
S
S
L
S
S
S
E
G
Rhesus Macaque
Macaca mulatta
XP_001087083
772
84726
S488
L
D
S
S
H
S
P
S
S
L
S
S
S
E
G
Dog
Lupus familis
XP_851865
781
85498
S497
S
L
S
S
S
E
G
S
S
S
S
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61985
741
81527
S457
L
S
L
D
S
S
H
S
P
S
S
L
S
S
S
Rat
Rattus norvegicus
O54968
604
67684
E356
S
P
S
R
A
S
P
E
H
S
V
E
S
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513064
403
43791
S147
S
S
S
S
S
S
S
S
S
S
S
S
S
S
S
Chicken
Gallus gallus
Q5ZL67
772
85168
S488
L
S
L
D
S
G
H
S
P
A
S
L
S
S
S
Frog
Xenopus laevis
NP_001080013
718
79943
S460
G
S
E
S
S
T
S
S
S
C
S
S
S
S
S
Zebra Danio
Brachydanio rerio
XP_001920265
797
88024
P514
S
S
H
S
P
A
S
P
S
N
S
E
T
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20482
1383
147394
S1029
A
A
A
T
A
V
Q
S
Q
S
I
K
Y
E
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
99.7
96
N.A.
93.1
27.7
N.A.
40.6
83.8
62.1
59
N.A.
23.5
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
100
97.3
N.A.
94.6
44.4
N.A.
45.8
90.5
74.2
73.9
N.A.
34.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
33.3
26.6
N.A.
53.3
26.6
40
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
33.3
26.6
N.A.
53.3
26.6
46.6
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
19
10
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
0
28
0
19
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
10
0
0
0
19
0
37
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
28
% G
% His:
0
0
10
0
28
0
19
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
46
10
19
0
0
0
0
0
0
28
0
19
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
37
10
19
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
37
46
55
64
46
55
28
82
64
46
82
55
82
64
46
% S
% Thr:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _