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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WFDC2
All Species:
4.85
Human Site:
S53
Identified Species:
13.33
UniProt:
Q14508
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14508
NP_006094.3
124
12993
S53
T
Q
E
C
V
S
D
S
E
C
A
D
N
L
K
Chimpanzee
Pan troglodytes
A4K2N9
123
13294
S53
P
D
Q
C
V
E
D
S
Q
C
P
L
T
R
K
Rhesus Macaque
Macaca mulatta
A4K2T2
123
13376
S53
P
D
Q
C
V
E
D
S
Q
C
P
L
T
R
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAU7
174
18013
K53
V
L
E
C
T
L
D
K
D
C
A
D
N
R
K
Rat
Rattus norvegicus
Q8CHN3
168
17430
N53
V
K
A
C
I
L
D
N
D
C
Q
D
N
Y
K
Wallaby
Macropus eugenll
Q9N0L8
191
21115
A50
K
Q
L
C
N
D
D
A
S
C
P
Q
N
M
R
Platypus
Ornith. anatinus
NP_001095134
124
12858
G53
T
E
D
C
L
S
D
G
D
C
P
D
T
S
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392394
158
17716
C46
S
C
F
S
D
S
H
C
L
G
I
G
K
C
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202083
210
21458
G92
D
N
K
C
C
S
N
G
C
G
L
S
C
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
32.2
N.A.
N.A.
44.8
45.2
24
58.8
N.A.
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
24.7
Protein Similarity:
100
41.1
40.3
N.A.
N.A.
51.1
53.5
32.4
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
37.1
P-Site Identity:
100
40
40
N.A.
N.A.
53.3
40
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
53.3
53.3
N.A.
N.A.
60
66.6
53.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
12
0
0
23
0
0
0
0
% A
% Cys:
0
12
0
89
12
0
0
12
12
78
0
0
12
12
12
% C
% Asp:
12
23
12
0
12
12
78
0
34
0
0
45
0
0
0
% D
% Glu:
0
12
23
0
0
23
0
0
12
0
0
0
0
0
12
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
23
0
23
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
12
12
12
0
0
0
0
12
0
0
0
0
12
0
67
% K
% Leu:
0
12
12
0
12
23
0
0
12
0
12
23
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
12
0
0
12
0
12
12
0
0
0
0
45
0
0
% N
% Pro:
23
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% P
% Gln:
0
23
23
0
0
0
0
0
23
0
12
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
12
% R
% Ser:
12
0
0
12
0
45
0
34
12
0
0
12
0
12
0
% S
% Thr:
23
0
0
0
12
0
0
0
0
0
0
0
34
0
0
% T
% Val:
23
0
0
0
34
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _