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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT1 All Species: 7.58
Human Site: S4479 Identified Species: 16.67
UniProt: Q14517 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14517 NP_005236.2 4590 506278 S4479 A A G S L G S S S R N R Q R F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001084587 4609 507875 L4498 P V S L A S T L S P D C R R R
Dog Lupus familis XP_532835 4692 518122 S4507 A A G S L G S S S R N R Q R F
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 M4444 P T S L T S T M S P D C R R R
Rat Rattus norvegicus Q8R508 4555 502069 M4444 P T S L T G T M S P D C R R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 Y4163 R A P I P P R Y S N Q N L E D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998132 4610 506620 L4496 S I R H R P P L P Q L Y S L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 S4594 P F M L P R S S N Q P L S R L
Honey Bee Apis mellifera XP_394631 3607 400577 H3497 H P N S Y L P H Y N I H T D T
Nematode Worm Caenorhab. elegans Q19319 4292 477180 S4182 L S S L R D S S D E W M G I D
Sea Urchin Strong. purpuratus XP_785422 3852 424350 L3742 D D Y G G L P L N A I N M R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 51.7 88.9 N.A. 51.6 51.7 N.A. 43.2 N.A. N.A. 64.4 N.A. 36.3 32.3 27.9 22.4
Protein Similarity: 100 N.A. 69.3 93.4 N.A. 69.3 69.2 N.A. 61.1 N.A. N.A. 80 N.A. 55.7 47.6 47.9 39.7
P-Site Identity: 100 N.A. 13.3 100 N.A. 13.3 20 N.A. 13.3 N.A. N.A. 0 N.A. 20 6.6 13.3 6.6
P-Site Similarity: 100 N.A. 33.3 100 N.A. 33.3 40 N.A. 13.3 N.A. N.A. 13.3 N.A. 33.3 6.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 28 0 0 10 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % C
% Asp: 10 10 0 0 0 10 0 0 10 0 28 0 0 10 19 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 19 % F
% Gly: 0 0 19 10 10 28 0 0 0 0 0 0 10 0 0 % G
% His: 10 0 0 10 0 0 0 10 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 0 0 0 19 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 46 19 19 0 28 0 0 10 10 10 10 10 % L
% Met: 0 0 10 0 0 0 0 19 0 0 0 10 10 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 19 19 19 19 0 0 0 % N
% Pro: 37 10 10 0 19 19 28 0 10 28 10 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 19 10 0 19 0 0 % Q
% Arg: 10 0 10 0 19 10 10 0 0 19 0 19 28 64 28 % R
% Ser: 10 10 37 28 0 19 37 37 55 0 0 0 19 0 0 % S
% Thr: 0 19 0 0 19 0 28 0 0 0 0 0 10 0 19 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 10 0 10 0 0 10 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _