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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT1
All Species:
16.97
Human Site:
Y468
Identified Species:
37.33
UniProt:
Q14517
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14517
NP_005236.2
4590
506278
Y468
P
E
F
T
Q
T
A
Y
K
A
A
F
D
E
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084587
4609
507875
Y529
P
E
F
Q
Q
P
L
Y
D
A
N
V
N
E
S
Dog
Lupus familis
XP_532835
4692
518122
Y468
P
E
F
T
Q
T
A
Y
K
A
S
F
D
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
Y476
P
E
F
Q
E
A
L
Y
E
T
F
V
N
E
S
Rat
Rattus norvegicus
Q8R508
4555
502069
Y476
P
E
F
Q
E
T
L
Y
E
T
F
V
N
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
H345
T
G
K
L
S
A
I
H
R
G
R
H
E
L
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998132
4610
506620
Y466
P
E
F
K
Q
T
S
Y
K
A
S
L
D
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
K509
P
I
F
E
N
V
N
K
V
I
S
I
N
E
N
Honey Bee
Apis mellifera
XP_394631
3607
400577
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
I362
S
I
S
K
K
P
V
I
P
T
N
E
T
V
T
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51.7
88.9
N.A.
51.6
51.7
N.A.
43.2
N.A.
N.A.
64.4
N.A.
36.3
32.3
27.9
22.4
Protein Similarity:
100
N.A.
69.3
93.4
N.A.
69.3
69.2
N.A.
61.1
N.A.
N.A.
80
N.A.
55.7
47.6
47.9
39.7
P-Site Identity:
100
N.A.
46.6
93.3
N.A.
33.3
40
N.A.
0
N.A.
N.A.
73.3
N.A.
26.6
0
0
0
P-Site Similarity:
100
N.A.
60
100
N.A.
60
66.6
N.A.
20
N.A.
N.A.
86.6
N.A.
40
0
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
19
0
0
37
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
28
0
0
% D
% Glu:
0
55
0
10
19
0
0
0
19
0
0
10
10
64
0
% E
% Phe:
0
0
64
0
0
0
0
0
0
0
19
19
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
19
0
0
0
0
10
10
0
10
0
10
0
0
0
% I
% Lys:
0
0
10
19
10
0
0
10
28
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
28
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
0
0
19
0
37
0
37
% N
% Pro:
64
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
28
37
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% R
% Ser:
10
0
10
0
10
0
10
0
0
0
28
0
0
0
28
% S
% Thr:
10
0
0
19
0
37
0
0
0
28
0
0
10
0
10
% T
% Val:
0
0
0
0
0
10
10
0
10
0
0
28
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _