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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIC1
All Species:
18.79
Human Site:
S449
Identified Species:
51.67
UniProt:
Q14526
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14526
NP_001091672
733
76468
S449
C
G
K
G
F
P
S
S
E
Q
L
N
A
H
V
Chimpanzee
Pan troglodytes
XP_515003
615
66212
E398
P
P
Y
P
C
K
E
E
E
E
N
G
K
D
A
Rhesus Macaque
Macaca mulatta
XP_001117386
733
77165
S449
C
G
K
G
F
P
S
S
E
Q
L
N
A
H
V
Dog
Lupus familis
XP_548318
732
76528
S448
C
G
K
G
F
P
S
S
E
Q
L
N
A
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1Y5
892
94303
S608
C
G
K
G
F
P
S
S
E
Q
L
N
A
H
V
Rat
Rattus norvegicus
A0JPL0
549
63545
A331
I
C
S
Q
C
G
K
A
F
R
Q
K
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90850
676
73740
S432
C
G
K
G
F
P
S
S
E
Q
L
N
A
H
V
Frog
Xenopus laevis
NP_001090444
458
50514
S241
V
S
A
S
V
A
N
S
A
S
Y
E
D
L
D
Zebra Danio
Brachydanio rerio
Q90W33
560
62581
E343
V
S
F
Q
C
K
D
E
E
E
G
L
E
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.1
74.4
96.7
N.A.
78.2
20.4
N.A.
N.A.
66.5
26
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
48.7
77.9
97.1
N.A.
78.9
33.9
N.A.
N.A.
72
36.9
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
N.A.
100
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
20
N.A.
N.A.
100
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
12
0
12
12
0
0
0
56
12
12
% A
% Cys:
56
12
0
0
34
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
12
12
12
% D
% Glu:
0
0
0
0
0
0
12
23
78
23
0
12
12
0
0
% E
% Phe:
0
0
12
0
56
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
56
0
56
0
12
0
0
0
0
12
12
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
56
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
56
0
0
23
12
0
0
0
0
12
12
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
56
12
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
12
56
0
12
0
% N
% Pro:
12
12
0
12
0
56
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
23
0
0
0
0
0
56
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
23
12
12
0
0
56
67
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% T
% Val:
23
0
0
0
12
0
0
0
0
0
0
0
0
0
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _