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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT81 All Species: 37.27
Human Site: S258 Identified Species: 91.11
UniProt: Q14533 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14533 NP_002272.2 505 54971 S258 Q S H I S D T S V V V K L D N
Chimpanzee Pan troglodytes A5A6M8 592 62520 S324 Q T H V S D T S V V L S M D N
Rhesus Macaque Macaca mulatta XP_001093214 505 54939 S258 Q S H I S D T S V V V K L D N
Dog Lupus familis XP_543657 513 55762 S258 H A H I S D T S V I V K M D N
Cat Felis silvestris
Mouse Mus musculus P97861 486 53233 S258 H S H I S D T S I V V K M D N
Rat Rattus norvegicus Q6IG05 542 59008 S294 Q N Q V S D T S V V L S M D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514791 516 55880 S260 Q A H I S D T S V I V K M D N
Chicken Gallus gallus O93532 492 53785 S266 Q A Q I S D T S V V L S M D N
Frog Xenopus laevis P16878 513 55433 S281 Q E Q I S D T S V V L S M D N
Zebra Danio Brachydanio rerio Q6NWF6 520 57741 S267 Q S Q I K D T S V V V E M D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.2 98.6 89.6 N.A. 82.9 49.4 N.A. 84.1 50.6 50.2 45 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 60.6 99.8 93.5 N.A. 89.6 63.8 N.A. 91.4 66.9 65.5 62.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 100 73.3 N.A. 80 60 N.A. 80 66.6 66.6 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 93.3 N.A. 93.3 86.6 N.A. 100 86.6 80 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 100 0 0 0 0 0 0 0 100 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 20 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 80 0 0 0 0 10 20 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 50 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 40 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 100 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 80 0 40 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 40 0 0 90 0 0 100 0 0 0 40 0 0 0 % S
% Thr: 0 10 0 0 0 0 100 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 20 0 0 0 0 90 80 60 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _