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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SQLE All Species: 16.97
Human Site: T116 Identified Species: 33.94
UniProt: Q14534 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14534 NP_003120 574 63923 T116 L I G T A A C T S T S S Q N D
Chimpanzee Pan troglodytes XP_519950 574 63793 T116 L I G A A A C T S T S S Q N D
Rhesus Macaque Macaca mulatta XP_001102258 571 63690 T116 L I G A A A S T S T S S Q N D
Dog Lupus familis XP_850640 573 63904 S116 L I G A A A S S I P S Q N D P
Cat Felis silvestris
Mouse Mus musculus P52019 572 63751 T116 G A A T S V S T S F V T D P E
Rat Rattus norvegicus P52020 573 64006 S116 T G A A T S V S T S S V T D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508800 574 63406 T116 P P G A A A S T P A M P R H D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103509 557 62024 G116 E V I I V G A G V L G S A M A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307300 526 57241 E115 G G Y L K L I E L G L E D C V
Maize Zea mays NP_001151921 539 57159 Q118 R I V G E L L Q P G G Y L K L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65404 516 56587 D104 L S K L G L E D C L E G I D A
Baker's Yeast Sacchar. cerevisiae P32476 496 55107 Y85 S I N N I E A Y P V T G Y T V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 92.1 87.6 N.A. 84.1 83.8 N.A. 78.2 N.A. N.A. 63.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 95.6 94.2 N.A. 91.8 91.9 N.A. 87.1 N.A. N.A. 78.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 86.6 40 N.A. 20 6.6 N.A. 33.3 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 53.3 N.A. 40 40 N.A. 46.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 40.7 40.5 N.A. 35 30.8 N.A.
Protein Similarity: 57.8 56.9 N.A. 52.9 47.9 N.A.
P-Site Identity: 0 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: 0 6.6 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 42 42 42 17 0 0 9 0 0 9 0 17 % A
% Cys: 0 0 0 0 0 0 17 0 9 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 9 0 0 0 0 17 25 34 % D
% Glu: 9 0 0 0 9 9 9 9 0 0 9 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 17 17 42 9 9 9 0 9 0 17 17 17 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 50 9 9 9 0 9 0 9 0 0 0 9 0 0 % I
% Lys: 0 0 9 0 9 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 42 0 0 17 0 25 9 0 9 17 9 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % M
% Asn: 0 0 9 9 0 0 0 0 0 0 0 0 9 25 0 % N
% Pro: 9 9 0 0 0 0 0 0 25 9 0 9 0 9 17 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 9 25 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 9 9 0 0 9 9 34 17 34 9 42 34 0 0 0 % S
% Thr: 9 0 0 17 9 0 0 42 9 25 9 9 9 9 0 % T
% Val: 0 9 9 0 9 9 9 0 9 9 9 9 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 9 0 0 0 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _