Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SQLE All Species: 22.42
Human Site: T150 Identified Species: 44.85
UniProt: Q14534 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14534 NP_003120 574 63923 T150 S R D G R K V T V I E R D L K
Chimpanzee Pan troglodytes XP_519950 574 63793 T150 S R D G R K V T V I E R D L K
Rhesus Macaque Macaca mulatta XP_001102258 571 63690 T150 S R D G R K V T V I E R D L K
Dog Lupus familis XP_850640 573 63904 T149 S R D G R K V T V I E R D L K
Cat Felis silvestris
Mouse Mus musculus P52019 572 63751 E151 G R K V T V I E R D L K E P D
Rat Rattus norvegicus P52020 573 64006 T149 S R D G R T V T V I E R D L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508800 574 63406 T150 S R D G R K V T V I E R D L K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103509 557 62024 Q152 R I V G E L L Q P G G F R V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307300 526 57241 L148 H T R L S Y P L E K F H S N V
Maize Zea mays NP_001151921 539 57159 G151 G Y A L F K D G R N T K L A Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65404 516 56587 F137 F P V D N N N F P F D P S A R
Baker's Yeast Sacchar. cerevisiae P32476 496 55107 L118 K V E K L K D L V K D G N D K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 92.1 87.6 N.A. 84.1 83.8 N.A. 78.2 N.A. N.A. 63.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 95.6 94.2 N.A. 91.8 91.9 N.A. 87.1 N.A. N.A. 78.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 93.3 N.A. 100 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 26.6 93.3 N.A. 100 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 40.7 40.5 N.A. 35 30.8 N.A.
Protein Similarity: 57.8 56.9 N.A. 52.9 47.9 N.A.
P-Site Identity: 0 6.6 N.A. 0 20 N.A.
P-Site Similarity: 0 13.3 N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 9 0 0 17 0 0 9 17 0 50 9 9 % D
% Glu: 0 0 9 0 9 0 0 9 9 0 50 0 9 0 0 % E
% Phe: 9 0 0 0 9 0 0 9 0 9 9 9 0 0 0 % F
% Gly: 17 0 0 59 0 0 0 9 0 9 9 9 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 9 0 0 0 0 9 0 0 50 0 0 0 0 0 % I
% Lys: 9 0 9 9 0 59 0 0 0 17 0 17 0 0 59 % K
% Leu: 0 0 0 17 9 9 9 17 0 0 9 0 9 50 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 9 9 0 0 9 0 0 9 9 0 % N
% Pro: 0 9 0 0 0 0 9 0 17 0 0 9 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 9 59 9 0 50 0 0 0 17 0 0 50 9 0 9 % R
% Ser: 50 0 0 0 9 0 0 0 0 0 0 0 17 0 0 % S
% Thr: 0 9 0 0 9 9 0 50 0 0 9 0 0 0 0 % T
% Val: 0 9 17 9 0 9 50 0 59 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _