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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SQLE
All Species:
30.3
Human Site:
Y359
Identified Species:
60.61
UniProt:
Q14534
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14534
NP_003120
574
63923
Y359
M
P
R
N
L
R
E
Y
M
V
E
K
I
Y
P
Chimpanzee
Pan troglodytes
XP_519950
574
63793
Y359
M
P
R
N
L
R
E
Y
M
V
E
K
I
Y
P
Rhesus Macaque
Macaca mulatta
XP_001102258
571
63690
Y356
M
P
R
N
L
R
E
Y
M
V
E
K
I
Y
P
Dog
Lupus familis
XP_850640
573
63904
Y358
M
P
R
N
L
R
E
Y
M
A
E
K
I
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
P52019
572
63751
Y357
L
P
R
N
L
R
E
Y
M
A
E
Q
I
Y
P
Rat
Rattus norvegicus
P52020
573
64006
Y358
L
P
R
N
L
R
E
Y
M
T
E
Q
I
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508800
574
63406
Y359
M
P
R
N
L
R
D
Y
M
V
E
R
I
Y
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103509
557
62024
Y342
M
P
R
D
L
M
Q
Y
M
T
D
K
I
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307300
526
57241
A319
V
Y
D
A
F
L
A
A
V
D
K
G
N
I
R
Maize
Zea mays
NP_001151921
539
57159
I324
A
P
Q
I
P
P
E
I
Y
D
S
F
I
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65404
516
56587
G309
F
L
K
G
I
D
E
G
E
H
I
K
A
M
P
Baker's Yeast
Sacchar. cerevisiae
P32476
496
55107
K289
D
I
K
S
W
M
I
K
D
V
Q
P
F
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
92.1
87.6
N.A.
84.1
83.8
N.A.
78.2
N.A.
N.A.
63.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
95.6
94.2
N.A.
91.8
91.9
N.A.
87.1
N.A.
N.A.
78.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
86.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
40.7
40.5
N.A.
35
30.8
N.A.
Protein Similarity:
57.8
56.9
N.A.
52.9
47.9
N.A.
P-Site Identity:
0
20
N.A.
20
13.3
N.A.
P-Site Similarity:
20
26.6
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
9
9
0
17
0
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
0
9
9
0
9
17
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
67
0
9
0
59
0
0
0
0
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
9
9
0
9
9
0
0
9
0
75
17
0
% I
% Lys:
0
0
17
0
0
0
0
9
0
0
9
50
0
0
0
% K
% Leu:
17
9
0
0
67
9
0
0
0
0
0
0
0
0
0
% L
% Met:
50
0
0
0
0
17
0
0
67
0
0
0
0
9
0
% M
% Asn:
0
0
0
59
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
75
0
0
9
9
0
0
0
0
0
9
0
0
84
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
9
17
0
0
0
% Q
% Arg:
0
0
67
0
0
59
0
0
0
0
0
9
0
0
9
% R
% Ser:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
9
42
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
67
9
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _