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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNF4G
All Species:
32.12
Human Site:
S118
Identified Species:
58.89
UniProt:
Q14541
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14541
NP_004124.4
408
45877
S118
E
V
R
S
R
Q
I
S
V
S
S
P
G
S
S
Chimpanzee
Pan troglodytes
XP_528171
454
51091
S164
E
V
R
S
R
Q
I
S
V
S
S
P
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001087848
454
51130
S164
E
V
R
S
R
Q
I
S
V
S
S
P
G
S
S
Dog
Lupus familis
XP_544134
455
51150
S165
E
I
R
S
R
Q
I
S
V
S
S
P
G
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU6
408
45878
S118
E
V
R
S
C
Q
I
S
V
P
S
P
S
S
S
Rat
Rattus norvegicus
P22449
474
52693
T166
E
V
L
S
Q
Q
I
T
S
P
I
S
G
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507309
419
46844
T166
E
A
L
S
Q
Q
I
T
S
P
V
P
G
L
S
Chicken
Gallus gallus
XP_425924
453
50647
S164
E
A
L
S
R
Q
I
S
V
S
S
P
G
A
S
Frog
Xenopus laevis
Q91766
464
51948
T166
E
V
L
S
Q
Q
I
T
S
S
V
G
V
L
N
Zebra Danio
Brachydanio rerio
NP_919349
454
50703
S157
D
V
L
S
R
Q
I
S
S
P
G
P
I
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49866
666
71882
A216
S
R
Q
S
K
A
G
A
A
M
E
P
N
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44960
369
41820
L125
I
V
P
D
D
P
L
L
D
T
L
I
R
A
E
Sea Urchin
Strong. purpuratus
XP_780389
468
51669
P137
H
M
S
R
Q
V
I
P
N
P
V
N
L
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
89.6
87
N.A.
95.8
64.5
N.A.
69.2
79
68.3
68
N.A.
38.8
N.A.
36.5
55.3
Protein Similarity:
100
89.8
89.6
88.3
N.A.
97.7
73.8
N.A.
79.7
84.7
76.9
78.1
N.A.
49.4
N.A.
53.6
70.5
P-Site Identity:
100
100
100
86.6
N.A.
80
40
N.A.
46.6
80
40
46.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
60
N.A.
60
86.6
60
60
N.A.
40
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
8
0
8
8
0
0
0
0
24
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
70
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
8
8
54
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
85
0
0
0
8
8
8
16
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
39
0
0
0
8
8
0
0
8
0
8
24
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
31
% N
% Pro:
0
0
8
0
0
8
0
8
0
39
0
70
0
8
0
% P
% Gln:
0
0
8
0
31
77
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
39
8
47
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
85
0
0
0
54
31
47
47
8
8
31
54
% S
% Thr:
0
0
0
0
0
0
0
24
0
8
0
0
0
0
0
% T
% Val:
0
62
0
0
0
8
0
0
47
0
24
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _