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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNF4G
All Species:
19.09
Human Site:
S395
Identified Species:
35
UniProt:
Q14541
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14541
NP_004124.4
408
45877
S395
K
I
A
A
N
Q
A
S
V
I
S
H
Q
H
L
Chimpanzee
Pan troglodytes
XP_528171
454
51091
S441
K
I
A
A
N
Q
A
S
V
I
S
H
Q
H
L
Rhesus Macaque
Macaca mulatta
XP_001087848
454
51130
S441
K
I
A
A
N
Q
A
S
V
I
S
H
Q
H
L
Dog
Lupus familis
XP_544134
455
51150
S442
K
I
A
A
N
Q
A
S
V
I
S
H
Q
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU6
408
45878
S395
K
I
T
A
N
Q
A
S
V
I
S
H
Q
S
L
Rat
Rattus norvegicus
P22449
474
52693
E444
P
P
S
G
S
G
S
E
S
Y
K
L
L
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507309
419
46844
T407
P
N
V
I
V
A
N
T
M
P
S
H
L
A
N
Chicken
Gallus gallus
XP_425924
453
50647
V441
M
S
S
N
Q
A
S
V
I
A
Q
Q
S
I
L
Frog
Xenopus laevis
Q91766
464
51948
A444
K
I
V
H
G
T
I
A
S
I
N
K
Q
P
T
Zebra Danio
Brachydanio rerio
NP_919349
454
50703
A434
K
M
A
S
G
V
I
A
T
V
P
K
Q
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49866
666
71882
P564
E
S
S
Y
L
D
M
P
V
K
H
Y
N
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44960
369
41820
T357
L
P
N
E
G
K
N
T
T
D
K
T
S
P
P
Sea Urchin
Strong. purpuratus
XP_780389
468
51669
H426
A
V
T
V
P
Q
T
H
I
V
T
H
P
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
89.6
87
N.A.
95.8
64.5
N.A.
69.2
79
68.3
68
N.A.
38.8
N.A.
36.5
55.3
Protein Similarity:
100
89.8
89.6
88.3
N.A.
97.7
73.8
N.A.
79.7
84.7
76.9
78.1
N.A.
49.4
N.A.
53.6
70.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
13.3
6.6
26.6
20
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
20
N.A.
26.6
26.6
40
46.6
N.A.
26.6
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
39
39
0
16
39
16
0
8
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
24
8
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
8
0
0
0
8
0
0
8
54
0
24
0
% H
% Ile:
0
47
0
8
0
0
16
0
16
47
0
0
0
8
0
% I
% Lys:
54
0
0
0
0
8
0
0
0
8
16
16
0
0
0
% K
% Leu:
8
0
0
0
8
0
0
0
0
0
0
8
16
0
47
% L
% Met:
8
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
39
0
16
0
0
0
8
0
8
0
8
% N
% Pro:
16
16
0
0
8
0
0
8
0
8
8
0
8
39
8
% P
% Gln:
0
0
0
0
8
47
0
0
0
0
8
8
54
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
24
8
8
0
16
39
16
0
47
0
16
16
16
% S
% Thr:
0
0
16
0
0
8
8
16
16
0
8
8
0
0
8
% T
% Val:
0
8
16
8
8
8
0
8
47
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _