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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNF4G
All Species:
33.33
Human Site:
T373
Identified Species:
61.11
UniProt:
Q14541
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14541
NP_004124.4
408
45877
T373
D
Q
I
S
T
P
E
T
P
L
P
S
P
P
Q
Chimpanzee
Pan troglodytes
XP_528171
454
51091
T419
D
Q
I
S
T
P
E
T
P
L
P
S
P
P
Q
Rhesus Macaque
Macaca mulatta
XP_001087848
454
51130
T419
D
Q
I
S
T
P
E
T
P
L
P
S
P
P
Q
Dog
Lupus familis
XP_544134
455
51150
T420
D
Q
I
S
T
P
E
T
P
L
P
S
P
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU6
408
45878
T373
D
Q
I
A
T
P
E
T
P
L
P
S
P
P
Q
Rat
Rattus norvegicus
P22449
474
52693
R422
G
Q
M
C
E
W
P
R
P
R
G
Q
A
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507309
419
46844
T385
T
S
N
D
G
P
H
T
H
H
P
L
H
P
H
Chicken
Gallus gallus
XP_425924
453
50647
T419
E
Q
I
S
T
P
E
T
P
L
P
S
P
P
Q
Frog
Xenopus laevis
Q91766
464
51948
T422
G
Q
M
S
T
P
E
T
P
Q
P
S
P
P
A
Zebra Danio
Brachydanio rerio
NP_919349
454
50703
T412
G
Q
M
S
T
P
E
T
P
I
P
S
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49866
666
71882
S542
P
P
L
N
S
P
K
S
Q
H
Q
H
Q
Q
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44960
369
41820
L335
E
D
V
Q
L
A
K
L
F
G
L
A
S
I
D
Sea Urchin
Strong. purpuratus
XP_780389
468
51669
A404
S
Q
S
S
A
A
T
A
Q
V
I
A
D
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
89.6
87
N.A.
95.8
64.5
N.A.
69.2
79
68.3
68
N.A.
38.8
N.A.
36.5
55.3
Protein Similarity:
100
89.8
89.6
88.3
N.A.
97.7
73.8
N.A.
79.7
84.7
76.9
78.1
N.A.
49.4
N.A.
53.6
70.5
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
26.6
93.3
73.3
73.3
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
26.6
100
80
86.6
N.A.
40
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
16
0
8
0
0
0
16
8
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
8
0
8
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
16
0
0
0
8
0
62
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
24
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
8
16
0
8
8
0
16
% H
% Ile:
0
0
47
0
0
0
0
0
0
8
8
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
0
8
0
0
8
0
47
8
8
0
0
0
% L
% Met:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
0
77
8
0
70
0
70
0
62
70
0
% P
% Gln:
0
77
0
8
0
0
0
0
16
8
8
8
8
8
47
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
8
8
8
62
8
0
0
8
0
0
0
62
8
0
0
% S
% Thr:
8
0
0
0
62
0
8
70
0
0
0
0
0
0
16
% T
% Val:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _