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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA5
All Species:
36.97
Human Site:
T397
Identified Species:
58.1
UniProt:
Q14554
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14554
NP_006801.1
519
59594
T397
P
T
W
E
E
Q
Q
T
S
V
L
H
L
V
G
Chimpanzee
Pan troglodytes
XP_001151831
738
82015
T616
P
T
W
E
E
Q
Q
T
S
V
L
H
L
V
G
Rhesus Macaque
Macaca mulatta
XP_001112864
519
59600
T397
P
T
W
E
E
Q
Q
T
S
V
L
H
L
V
G
Dog
Lupus familis
XP_535765
658
74761
T536
P
T
W
E
E
Q
Q
T
S
V
L
H
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q921X9
517
59249
T395
P
T
W
E
E
Q
Q
T
S
V
L
H
L
V
G
Rat
Rattus norvegicus
Q5I0H9
517
59381
T395
P
T
W
E
E
Q
Q
T
S
V
L
H
L
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422097
531
60658
S409
P
A
W
E
E
K
Q
S
S
V
V
H
L
A
G
Frog
Xenopus laevis
NP_001086600
523
59535
S401
P
S
W
D
E
K
P
S
T
V
L
H
L
V
G
Zebra Danio
Brachydanio rerio
NP_001107048
528
60217
S406
K
S
W
D
E
M
P
S
S
V
S
H
L
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
P368
P
E
D
W
D
K
N
P
V
K
V
L
V
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34329
618
69779
P500
A
P
K
D
D
K
G
P
V
K
T
V
V
G
S
Sea Urchin
Strong. purpuratus
XP_001200162
553
61708
S423
P
A
W
S
D
V
P
S
A
V
N
H
L
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
P379
I
P
E
V
N
N
E
P
V
K
V
V
V
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
D270
A
G
I
V
E
S
L
D
A
L
V
K
E
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
T278
D
E
I
V
A
K
Y
T
G
G
A
S
L
A
E
Conservation
Percent
Protein Identity:
100
69.7
98.8
74.7
N.A.
89.9
90.3
N.A.
N.A.
73
64.6
63.2
N.A.
21.3
N.A.
20.3
32.1
Protein Similarity:
100
70
99
76.9
N.A.
95.5
95.9
N.A.
N.A.
84.7
81.8
80.8
N.A.
37.3
N.A.
36
48.8
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
66.6
60
40
N.A.
6.6
N.A.
0
40
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
93.3
60
N.A.
33.3
N.A.
26.6
60
Percent
Protein Identity:
N.A.
21.1
N.A.
21.1
N.A.
20.2
Protein Similarity:
N.A.
38.1
N.A.
34.4
N.A.
33.7
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
20
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
0
7
0
0
0
14
0
7
0
0
27
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
20
20
0
0
7
0
0
0
0
0
0
7
% D
% Glu:
0
14
7
47
67
0
7
0
0
0
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
7
0
7
7
0
0
0
14
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% H
% Ile:
7
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
7
0
0
34
0
0
0
20
0
7
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
7
47
7
74
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
7
0
0
0
7
0
0
0
0
% N
% Pro:
67
14
0
0
0
0
20
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
40
47
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
14
0
7
0
7
0
27
54
0
7
7
0
7
14
% S
% Thr:
0
40
0
0
0
0
0
47
7
0
7
0
0
7
0
% T
% Val:
0
0
0
20
0
7
0
0
20
67
27
14
20
40
7
% V
% Trp:
0
0
67
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _