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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA5
All Species:
27.58
Human Site:
T493
Identified Species:
43.33
UniProt:
Q14554
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14554
NP_006801.1
519
59594
T493
E
K
Y
D
S
D
R
T
E
L
G
F
T
N
Y
Chimpanzee
Pan troglodytes
XP_001151831
738
82015
T712
E
K
Y
D
S
D
R
T
E
L
G
F
T
N
Y
Rhesus Macaque
Macaca mulatta
XP_001112864
519
59600
T493
E
K
Y
D
S
D
R
T
E
L
G
F
T
N
Y
Dog
Lupus familis
XP_535765
658
74761
T632
E
K
Y
D
S
D
R
T
E
S
G
F
T
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q921X9
517
59249
T491
E
K
Y
E
S
D
R
T
E
L
G
F
T
S
F
Rat
Rattus norvegicus
Q5I0H9
517
59381
T491
E
K
Y
E
S
D
R
T
E
L
G
F
T
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422097
531
60658
G505
E
K
Y
T
G
E
R
G
E
A
G
F
T
T
F
Frog
Xenopus laevis
NP_001086600
523
59535
T497
E
K
Y
S
G
E
R
T
E
S
G
F
I
G
F
Zebra Danio
Brachydanio rerio
NP_001107048
528
60217
G502
E
K
Y
N
G
E
R
G
E
A
G
F
T
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
L458
N
K
V
I
D
F
N
L
D
R
T
L
D
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34329
618
69779
N594
E
P
I
K
Y
S
G
N
R
D
L
E
D
L
K
Sea Urchin
Strong. purpuratus
XP_001200162
553
61708
M517
E
K
Y
T
G
G
R
M
A
E
D
F
E
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
T472
T
S
Y
D
S
G
R
T
A
D
D
I
V
D
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
L347
S
P
V
K
A
D
E
L
T
L
K
R
N
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
R355
T
V
K
V
N
V
L
R
K
F
V
E
K
A
A
Conservation
Percent
Protein Identity:
100
69.7
98.8
74.7
N.A.
89.9
90.3
N.A.
N.A.
73
64.6
63.2
N.A.
21.3
N.A.
20.3
32.1
Protein Similarity:
100
70
99
76.9
N.A.
95.5
95.9
N.A.
N.A.
84.7
81.8
80.8
N.A.
37.3
N.A.
36
48.8
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
53.3
53.3
53.3
N.A.
6.6
N.A.
6.6
40
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
66.6
66.6
73.3
N.A.
26.6
N.A.
6.6
40
Percent
Protein Identity:
N.A.
21.1
N.A.
21.1
N.A.
20.2
Protein Similarity:
N.A.
38.1
N.A.
34.4
N.A.
33.7
P-Site Identity:
N.A.
33.3
N.A.
13.3
N.A.
0
P-Site Similarity:
N.A.
46.6
N.A.
20
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
14
14
0
0
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
7
47
0
0
7
14
14
0
14
14
0
% D
% Glu:
74
0
0
14
0
20
7
0
60
7
0
14
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
7
0
67
0
0
54
% F
% Gly:
0
0
0
0
27
14
7
14
0
0
60
0
0
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
0
0
0
0
0
0
7
7
7
0
% I
% Lys:
0
74
7
14
0
0
0
0
7
0
7
0
7
0
7
% K
% Leu:
0
0
0
0
0
0
7
14
0
40
7
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
7
0
7
7
0
0
0
0
7
20
0
% N
% Pro:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
74
7
7
7
0
7
0
0
0
% R
% Ser:
7
7
0
7
47
7
0
0
0
14
0
0
0
20
0
% S
% Thr:
14
0
0
14
0
0
0
54
7
0
7
0
54
7
0
% T
% Val:
0
7
14
7
0
7
0
0
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
74
0
7
0
0
0
0
0
0
0
0
0
27
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _