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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA5
All Species:
38.79
Human Site:
Y232
Identified Species:
60.95
UniProt:
Q14554
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14554
NP_006801.1
519
59594
Y232
R
G
F
P
T
I
C
Y
F
E
K
G
R
F
L
Chimpanzee
Pan troglodytes
XP_001151831
738
82015
Y451
R
G
F
P
T
I
C
Y
F
E
K
G
R
F
L
Rhesus Macaque
Macaca mulatta
XP_001112864
519
59600
Y232
R
G
F
P
T
I
C
Y
F
E
K
G
R
F
L
Dog
Lupus familis
XP_535765
658
74761
Y371
R
G
Y
P
T
I
C
Y
F
E
K
G
R
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q921X9
517
59249
Y230
R
G
Y
P
T
I
C
Y
F
E
K
G
R
F
L
Rat
Rattus norvegicus
Q5I0H9
517
59381
Y230
R
G
Y
P
T
I
C
Y
F
E
K
G
R
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422097
531
60658
Y243
R
G
Y
P
T
I
C
Y
F
E
K
G
K
F
L
Frog
Xenopus laevis
NP_001086600
523
59535
Y237
K
G
Y
P
T
V
L
Y
F
E
K
G
K
Y
M
Zebra Danio
Brachydanio rerio
NP_001107048
528
60217
Y240
K
G
Y
P
T
F
C
Y
F
E
K
G
K
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K227
L
N
E
E
N
L
K
K
F
A
Q
V
Q
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34329
618
69779
K226
V
S
G
Y
P
T
M
K
I
I
R
N
G
R
R
Sea Urchin
Strong. purpuratus
XP_001200162
553
61708
Y246
T
G
Y
P
T
I
K
Y
F
S
Y
G
K
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
V227
L
K
P
F
D
E
L
V
V
D
S
K
D
F
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
V134
N
K
E
G
G
T
N
V
K
L
A
A
V
P
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
L142
K
K
G
S
A
P
S
L
V
N
I
L
N
D
A
Conservation
Percent
Protein Identity:
100
69.7
98.8
74.7
N.A.
89.9
90.3
N.A.
N.A.
73
64.6
63.2
N.A.
21.3
N.A.
20.3
32.1
Protein Similarity:
100
70
99
76.9
N.A.
95.5
95.9
N.A.
N.A.
84.7
81.8
80.8
N.A.
37.3
N.A.
36
48.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
53.3
73.3
N.A.
13.3
N.A.
0
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
33.3
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
21.1
N.A.
21.1
N.A.
20.2
Protein Similarity:
N.A.
38.1
N.A.
34.4
N.A.
33.7
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
13.3
N.A.
0
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
7
7
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
7
0
0
7
7
7
% D
% Glu:
0
0
14
7
0
7
0
0
0
60
0
0
0
0
0
% E
% Phe:
0
0
20
7
0
7
0
0
74
0
0
0
0
60
0
% F
% Gly:
0
67
14
7
7
0
0
0
0
0
0
67
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
54
0
0
7
7
7
0
0
0
0
% I
% Lys:
20
20
0
0
0
0
14
14
7
0
60
7
27
0
0
% K
% Leu:
14
0
0
0
0
7
14
7
0
7
0
7
0
7
60
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
0
0
7
0
7
0
0
7
0
7
7
0
0
% N
% Pro:
0
0
7
67
7
7
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
7
% Q
% Arg:
47
0
0
0
0
0
0
0
0
0
7
0
40
7
7
% R
% Ser:
0
7
0
7
0
0
7
0
0
7
7
0
0
7
0
% S
% Thr:
7
0
0
0
67
14
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
7
0
14
14
0
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
7
0
0
0
67
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _