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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX8
All Species:
15.45
Human Site:
S226
Identified Species:
28.33
UniProt:
Q14562
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14562
NP_004932.1
1220
139315
S226
K
S
R
Y
R
S
R
S
R
S
Q
S
P
P
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S154
G
K
K
K
T
G
G
S
K
Q
Q
T
E
K
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537627
1216
138553
S222
K
S
R
Y
R
S
R
S
R
S
Q
S
P
P
K
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
S250
K
S
R
Y
R
S
R
S
R
S
Q
S
P
F
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418105
1076
123154
D186
R
S
R
S
R
T
R
D
R
N
R
G
K
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663993
1210
138002
S220
K
R
R
S
R
W
H
S
R
S
R
S
R
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610928
1242
141917
R219
S
R
S
R
D
N
R
R
R
S
R
S
R
E
D
Honey Bee
Apis mellifera
XP_623289
1192
136394
S205
R
S
R
D
R
K
R
S
R
S
R
D
R
K
F
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
R202
D
R
D
R
D
R
D
R
G
R
G
D
R
R
G
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002318357
1207
137837
R217
D
G
G
G
E
R
E
R
R
N
V
R
H
G
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
R195
E
D
R
R
R
D
R
R
A
K
D
E
Y
V
E
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
C205
F
G
T
R
M
K
N
C
D
G
L
V
H
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
N.A.
98.5
N.A.
96.8
N.A.
N.A.
N.A.
84
N.A.
91.1
N.A.
69.4
71.8
61.3
21.9
Protein Similarity:
100
59
N.A.
99.1
N.A.
97.3
N.A.
N.A.
N.A.
86.8
N.A.
94.5
N.A.
82
83.9
75.4
28.8
P-Site Identity:
100
13.3
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
33.3
N.A.
46.6
N.A.
26.6
46.6
0
0
P-Site Similarity:
100
33.3
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
66.6
N.A.
53.3
N.A.
40
60
0
0
Percent
Protein Identity:
59.1
N.A.
N.A.
59.3
44.2
N.A.
Protein Similarity:
75
N.A.
N.A.
75.4
62.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
16
8
8
8
16
8
8
8
8
0
8
16
0
0
8
% D
% Glu:
8
0
0
0
8
0
8
0
0
0
0
8
8
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
8
16
8
8
0
8
8
0
8
8
8
8
0
8
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
16
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
31
8
8
8
0
16
0
0
8
8
0
0
8
16
24
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
24
16
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
31
0
0
0
0
% Q
% Arg:
16
24
54
31
54
16
54
31
62
8
31
8
31
8
8
% R
% Ser:
8
39
8
16
0
24
0
47
0
47
0
39
0
16
8
% S
% Thr:
0
0
8
0
8
8
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
24
0
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _