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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX8
All Species:
28.79
Human Site:
S395
Identified Species:
52.78
UniProt:
Q14562
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14562
NP_004932.1
1220
139315
S395
R
K
R
L
T
R
I
S
D
P
E
K
W
E
I
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
K305
T
N
R
Y
H
M
P
K
E
T
R
G
Q
P
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537627
1216
138553
S391
R
K
R
L
T
R
I
S
D
P
E
K
W
E
I
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
S419
R
K
R
L
T
R
I
S
D
P
E
K
W
E
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418105
1076
123154
R337
T
N
E
E
T
S
M
R
N
P
D
R
P
S
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663993
1210
138002
S385
R
K
R
L
T
K
I
S
D
P
E
K
W
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610928
1242
141917
S417
R
K
R
V
T
R
I
S
S
P
E
R
W
E
I
Honey Bee
Apis mellifera
XP_623289
1192
136394
S368
K
R
V
Q
R
L
S
S
P
E
K
W
E
I
K
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
S366
G
K
A
R
V
R
I
S
T
P
E
R
W
E
L
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002318357
1207
137837
S385
R
R
P
L
K
R
M
S
S
P
E
K
W
E
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
S346
R
R
P
L
K
K
M
S
S
P
E
R
W
E
A
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
V361
D
E
T
D
E
I
D
V
E
L
N
T
D
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
N.A.
98.5
N.A.
96.8
N.A.
N.A.
N.A.
84
N.A.
91.1
N.A.
69.4
71.8
61.3
21.9
Protein Similarity:
100
59
N.A.
99.1
N.A.
97.3
N.A.
N.A.
N.A.
86.8
N.A.
94.5
N.A.
82
83.9
75.4
28.8
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
13.3
N.A.
93.3
N.A.
80
6.6
53.3
0
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
40
N.A.
100
N.A.
93.3
26.6
66.6
0
Percent
Protein Identity:
59.1
N.A.
N.A.
59.3
44.2
N.A.
Protein Similarity:
75
N.A.
N.A.
75.4
62.8
N.A.
P-Site Identity:
60
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
8
0
31
0
8
0
8
8
0
% D
% Glu:
0
8
8
8
8
0
0
0
16
8
62
0
8
62
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
47
0
0
0
0
0
0
8
39
% I
% Lys:
8
47
0
0
16
16
0
8
0
0
8
39
0
0
8
% K
% Leu:
0
0
0
47
0
8
0
0
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
8
24
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
16
0
0
0
8
0
8
70
0
0
8
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
54
24
47
8
8
47
0
8
0
0
8
31
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
70
24
0
0
0
0
8
0
% S
% Thr:
16
0
8
0
47
0
0
0
8
8
0
8
0
0
0
% T
% Val:
0
0
8
8
8
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
62
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _