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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX8 All Species: 32.42
Human Site: S799 Identified Species: 59.44
UniProt: Q14562 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14562 NP_004932.1 1220 139315 S799 I L Y E R M K S L G P D V P E
Chimpanzee Pan troglodytes Q7YR39 1044 119631 L646 G S K I R E L L V L P I Y A N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537627 1216 138553 S795 I L Y E R M K S L G P D V P E
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 S823 I L Y E R M K S L G P D V P E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418105 1076 123154 T678 A L P S E M Q T R I F D P A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663993 1210 138002 S789 I L Y E R M K S L G P D V P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610928 1242 141917 S820 I L Y E R M K S L G P D V P E
Honey Bee Apis mellifera XP_623289 1192 136394 S770 I L Y E R M K S L G P D V P E
Nematode Worm Caenorhab. elegans Q09530 1200 135741 S774 V L Y E R M K S M G P D V P E
Sea Urchin Strong. purpuratus O17438 455 51461 V57 Q R S D L K L V V M S A T L D
Poplar Tree Populus trichocarpa XP_002318357 1207 137837 G788 S L Y E R M K G L G K N V P E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 G749 S L Y E R M K G L G K N V P E
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 T717 I L Y D R V K T L G D S I G E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40 N.A. 98.5 N.A. 96.8 N.A. N.A. N.A. 84 N.A. 91.1 N.A. 69.4 71.8 61.3 21.9
Protein Similarity: 100 59 N.A. 99.1 N.A. 97.3 N.A. N.A. N.A. 86.8 N.A. 94.5 N.A. 82 83.9 75.4 28.8
P-Site Identity: 100 13.3 N.A. 100 N.A. 100 N.A. N.A. N.A. 20 N.A. 100 N.A. 100 100 86.6 0
P-Site Similarity: 100 20 N.A. 100 N.A. 100 N.A. N.A. N.A. 33.3 N.A. 100 N.A. 100 100 100 20
Percent
Protein Identity: 59.1 N.A. N.A. 59.3 44.2 N.A.
Protein Similarity: 75 N.A. N.A. 75.4 62.8 N.A.
P-Site Identity: 73.3 N.A. N.A. 73.3 53.3 N.A.
P-Site Similarity: 80 N.A. N.A. 80 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 8 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 16 0 0 0 0 0 0 8 62 0 0 8 % D
% Glu: 0 0 0 70 8 8 0 0 0 0 0 0 0 0 77 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 16 0 77 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 54 0 0 8 0 0 0 0 0 8 0 8 8 0 0 % I
% Lys: 0 0 8 0 0 8 77 0 0 0 16 0 0 0 0 % K
% Leu: 0 85 0 0 8 0 16 8 70 8 0 0 0 8 0 % L
% Met: 0 0 0 0 0 77 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 8 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 62 0 8 70 8 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 85 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 16 8 8 8 0 0 0 54 0 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 16 0 0 0 0 8 0 0 % T
% Val: 8 0 0 0 0 8 0 8 16 0 0 0 70 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 77 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _