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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX8
All Species:
9.09
Human Site:
Y241
Identified Species:
16.67
UniProt:
Q14562
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14562
NP_004932.1
1220
139315
Y241
D
R
K
D
R
D
K
Y
G
E
R
N
L
D
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
R169
E
S
E
D
E
W
E
R
T
E
R
E
R
L
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537627
1216
138553
Y237
D
R
K
D
R
D
K
Y
G
E
R
N
L
D
R
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
Y265
D
R
K
D
R
E
K
Y
G
E
R
N
L
D
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418105
1076
123154
R201
Y
Y
S
R
S
R
S
R
S
P
S
R
D
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663993
1210
138002
G235
A
R
T
D
R
D
K
G
S
D
R
W
K
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610928
1242
141917
R234
R
D
R
D
R
D
R
R
H
K
S
S
S
S
R
Honey Bee
Apis mellifera
XP_623289
1192
136394
K220
H
K
D
R
Y
S
N
K
S
D
R
S
R
S
R
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
R217
D
D
R
Q
R
D
R
R
D
R
R
D
D
G
G
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002318357
1207
137837
E196
D
R
E
D
G
E
G
E
R
E
R
R
N
V
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
E210
E
D
K
G
G
A
N
E
P
E
L
Y
Q
V
Y
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
L220
E
M
S
D
Q
R
T
L
D
P
H
D
V
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
N.A.
98.5
N.A.
96.8
N.A.
N.A.
N.A.
84
N.A.
91.1
N.A.
69.4
71.8
61.3
21.9
Protein Similarity:
100
59
N.A.
99.1
N.A.
97.3
N.A.
N.A.
N.A.
86.8
N.A.
94.5
N.A.
82
83.9
75.4
28.8
P-Site Identity:
100
20
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
6.6
N.A.
46.6
N.A.
26.6
13.3
26.6
0
P-Site Similarity:
100
46.6
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
6.6
N.A.
60
N.A.
53.3
33.3
46.6
0
Percent
Protein Identity:
59.1
N.A.
N.A.
59.3
44.2
N.A.
Protein Similarity:
75
N.A.
N.A.
75.4
62.8
N.A.
P-Site Identity:
40
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
24
8
62
0
39
0
0
16
16
0
16
16
31
0
% D
% Glu:
24
0
16
0
8
16
8
16
0
47
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
16
0
8
8
24
0
0
0
0
8
8
% G
% His:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
31
0
0
0
31
8
0
8
0
0
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
0
24
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
24
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
16
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
8
39
16
16
47
16
16
31
8
8
62
16
16
8
62
% R
% Ser:
0
8
16
0
8
8
8
0
24
0
16
16
8
16
0
% S
% Thr:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
24
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
8
0
0
8
0
0
24
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _