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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX8 All Species: 39.39
Human Site: Y756 Identified Species: 72.22
UniProt: Q14562 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14562 NP_004932.1 1220 139315 Y756 T K E P E T D Y L D A S L I T
Chimpanzee Pan troglodytes Q7YR39 1044 119631 L603 E A C V V S V L Q I H V T Q P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537627 1216 138553 Y752 T K E P E T D Y L D A S L I T
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 Y780 T K E P E T D Y L D A S L I T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418105 1076 123154 F635 P P G D I L V F L T G Q E E I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663993 1210 138002 Y746 T K E P E T D Y L D A S L I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610928 1242 141917 Y777 T K E P E T D Y L D A S L I T
Honey Bee Apis mellifera XP_623289 1192 136394 Y727 T K E P E T D Y L D A A L I T
Nematode Worm Caenorhab. elegans Q09530 1200 135741 Y731 T R E P E S D Y L E A A H I T
Sea Urchin Strong. purpuratus O17438 455 51461 M14 G M L L R E G M T D P L L E R
Poplar Tree Populus trichocarpa XP_002318357 1207 137837 Y745 T K Q P E S D Y L D A S L I T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 Y706 T K Q P E T D Y L D A A L I T
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 Y674 S Q T P Q M D Y I E A A L D C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40 N.A. 98.5 N.A. 96.8 N.A. N.A. N.A. 84 N.A. 91.1 N.A. 69.4 71.8 61.3 21.9
Protein Similarity: 100 59 N.A. 99.1 N.A. 97.3 N.A. N.A. N.A. 86.8 N.A. 94.5 N.A. 82 83.9 75.4 28.8
P-Site Identity: 100 0 N.A. 100 N.A. 100 N.A. N.A. N.A. 6.6 N.A. 100 N.A. 100 93.3 66.6 13.3
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 N.A. N.A. N.A. 13.3 N.A. 100 N.A. 100 100 93.3 13.3
Percent
Protein Identity: 59.1 N.A. N.A. 59.3 44.2 N.A.
Protein Similarity: 75 N.A. N.A. 75.4 62.8 N.A.
P-Site Identity: 86.6 N.A. N.A. 86.6 33.3 N.A.
P-Site Similarity: 100 N.A. N.A. 100 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 77 31 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 0 0 77 0 0 70 0 0 0 8 0 % D
% Glu: 8 0 54 0 70 8 0 0 0 16 0 0 8 16 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 8 0 0 0 70 8 % I
% Lys: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 8 0 8 0 8 77 0 0 8 77 0 0 % L
% Met: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 77 0 0 0 0 0 0 8 0 0 0 8 % P
% Gln: 0 8 16 0 8 0 0 0 8 0 0 8 0 8 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 8 0 0 0 0 24 0 0 0 0 0 47 0 0 0 % S
% Thr: 70 0 8 0 0 54 0 0 8 8 0 0 8 0 70 % T
% Val: 0 0 0 8 8 0 16 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _