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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA3A
All Species:
36.67
Human Site:
S391
Identified Species:
80.67
UniProt:
Q14563
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14563
NP_006071.1
771
88889
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Chimpanzee
Pan troglodytes
XP_001160811
769
88874
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Rhesus Macaque
Macaca mulatta
XP_001096722
734
84680
S367
D
V
I
T
F
A
R
S
H
P
A
M
Y
N
P
Dog
Lupus familis
XP_849675
772
88877
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O08665
772
88781
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Rat
Rattus norvegicus
Q63548
772
88790
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506000
839
96323
S457
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Chicken
Gallus gallus
Q90607
772
88849
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
E
Frog
Xenopus laevis
NP_001079324
774
89301
S392
Q
T
F
G
G
F
D
S
T
K
D
L
P
D
E
Zebra Danio
Brachydanio rerio
Q9W686
778
88886
S392
K
T
F
D
G
F
E
S
T
K
D
F
P
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
K406
I
A
V
D
A
Q
I
K
T
P
G
G
K
T
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
93.5
95.5
N.A.
95.4
95.8
N.A.
85.3
88.4
84.5
76.2
N.A.
28.8
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
94.6
97.6
N.A.
98.3
98.5
N.A.
89.3
95.3
93.6
86.2
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
93.3
86.6
80
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
19
0
0
73
0
0
0
82
0
0
82
64
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
19
% E
% Phe:
0
0
82
0
10
82
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
73
82
0
0
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
73
0
0
0
0
0
0
10
0
82
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
19
0
0
82
0
10
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
91
0
0
0
0
0
0
0
% S
% Thr:
0
82
0
10
0
0
0
0
91
0
0
0
0
10
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _