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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
46.36
Human Site:
S515
Identified Species:
63.75
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
S515
G
H
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
S515
G
H
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
S515
G
H
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Dog
Lupus familis
XP_533338
955
107181
S649
G
H
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
S515
G
H
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Rat
Rattus norvegicus
Q62724
507
57351
I234
N
E
V
T
D
Y
A
I
A
R
R
I
V
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
S469
G
H
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Chicken
Gallus gallus
NP_001006527
916
103481
S516
G
R
Y
D
R
S
K
S
L
K
Q
N
I
N
L
Frog
Xenopus laevis
Q7ZY18
825
93359
S516
G
R
Y
D
R
A
K
S
L
K
Q
N
V
N
L
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
S513
G
R
Y
D
R
S
K
S
L
K
Q
N
V
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
S507
G
R
Y
D
R
S
K
S
L
Q
Q
N
I
Q
L
Honey Bee
Apis mellifera
XP_396515
813
91942
S508
G
R
Y
D
R
K
K
S
L
Q
Q
N
V
Q
L
Nematode Worm
Caenorhab. elegans
P34647
810
91112
P516
G
R
Y
D
R
S
R
P
L
K
Y
N
V
Q
M
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
P509
G
R
Y
D
K
T
K
P
L
K
Q
N
I
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
L476
S
L
L
S
R
F
D
L
L
F
I
V
L
D
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
D443
I
C
A
I
D
E
F
D
K
M
D
E
S
D
R
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
S694
G
R
Y
N
R
K
L
S
L
R
G
N
L
N
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
93.3
80
86.6
N.A.
80
66.6
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
93.3
93.3
93.3
N.A.
86.6
80
73.3
80
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
6.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
6
6
0
6
0
0
0
0
0
0
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
77
12
0
6
6
0
0
6
0
0
18
0
% D
% Glu:
0
6
0
0
0
6
0
0
0
0
0
6
0
0
0
% E
% Phe:
0
0
0
0
0
6
6
0
0
6
0
0
0
0
0
% F
% Gly:
83
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% G
% His:
0
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
6
0
0
0
6
0
0
6
6
53
0
0
% I
% Lys:
0
0
0
0
6
12
71
0
6
65
0
0
0
0
0
% K
% Leu:
0
6
6
0
0
0
6
6
89
0
0
0
12
0
77
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
12
% M
% Asn:
6
0
0
6
0
0
0
0
0
0
0
83
0
59
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
71
0
0
24
6
% Q
% Arg:
0
48
0
0
83
0
6
0
0
12
6
0
0
0
6
% R
% Ser:
6
0
0
6
0
59
0
71
0
0
0
0
6
0
0
% S
% Thr:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
6
0
0
0
0
0
0
0
0
6
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
83
0
0
6
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _