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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
36.36
Human Site:
S607
Identified Species:
50
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
S607
H
L
R
Q
R
D
G
S
G
V
T
K
S
S
W
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
S607
H
L
R
Q
R
D
G
S
G
V
T
K
S
S
W
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
S607
H
L
R
Q
R
D
G
S
G
V
T
K
S
S
W
Dog
Lupus familis
XP_533338
955
107181
S741
R
L
R
Q
R
D
G
S
G
V
T
K
S
S
W
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
S607
R
L
R
Q
R
D
G
S
G
V
T
K
S
S
W
Rat
Rattus norvegicus
Q62724
507
57351
E325
A
R
M
H
C
C
D
E
V
Q
P
K
H
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
S561
R
L
R
Q
R
D
G
S
G
V
T
K
S
S
W
Chicken
Gallus gallus
NP_001006527
916
103481
S608
R
L
R
Q
R
D
S
S
G
V
T
K
S
S
W
Frog
Xenopus laevis
Q7ZY18
825
93359
S608
R
L
R
Q
R
D
G
S
G
V
T
K
S
A
W
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
S605
R
L
R
Q
R
D
G
S
G
V
T
K
S
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
G599
H
L
R
Q
R
D
T
G
T
S
G
R
S
T
W
Honey Bee
Apis mellifera
XP_396515
813
91942
T600
L
L
R
Q
R
T
G
T
N
A
G
K
W
R
V
Nematode Worm
Caenorhab. elegans
P34647
810
91112
N610
K
L
R
M
S
D
S
N
N
A
A
T
S
S
W
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
G601
R
L
R
Q
R
D
S
G
S
T
T
S
S
W
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
L568
Y
I
H
Y
A
K
N
L
I
Q
P
R
L
T
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
H534
E
L
A
K
H
V
L
H
V
H
Q
T
E
E
S
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
Q786
E
L
R
K
D
D
A
Q
G
F
S
R
S
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
93.3
86.6
86.6
86.6
N.A.
53.3
40
40
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
93.3
86.6
93.3
93.3
N.A.
66.6
46.6
46.6
46.6
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
6
0
6
0
0
12
6
0
0
12
0
% A
% Cys:
0
0
0
0
6
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
77
6
0
0
0
0
0
0
0
6
% D
% Glu:
12
0
0
0
0
0
0
6
0
0
0
0
6
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
53
12
59
0
12
0
0
0
0
% G
% His:
24
0
6
6
6
0
0
6
0
6
0
0
6
0
0
% H
% Ile:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% I
% Lys:
6
0
0
12
0
6
0
0
0
0
0
65
0
0
6
% K
% Leu:
6
89
0
0
0
0
6
6
0
0
0
0
6
0
0
% L
% Met:
0
0
6
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
6
6
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
71
0
0
0
6
0
12
6
0
0
0
0
% Q
% Arg:
42
6
83
0
71
0
0
0
0
0
0
18
0
6
6
% R
% Ser:
0
0
0
0
6
0
18
53
6
6
6
6
77
53
6
% S
% Thr:
0
0
0
0
0
6
6
6
6
6
59
12
0
12
0
% T
% Val:
0
0
0
0
0
6
0
0
12
53
0
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
6
6
65
% W
% Tyr:
6
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _